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ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Struktur
503615-07-4
CAS-Nr.
503615-07-4
Englisch Name:
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Synonyma:
X5909;TECO-012;Apixaban Impurity 81;Apixaban interMediate;Intermediates of apixaban;Apixaban Impurity 11 ethyl;Apixaban Stage-II impurity;ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-te...;ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate;ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-ca
CBNumber:
CB82623113
Summenformel:
C22H22N4O4
Molgewicht:
406.43
MOL-Datei:
503615-07-4.mol

ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Eigenschaften

Siedepunkt:
651.6±55.0 °C(Predicted)
Dichte
1.34±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
L?slichkeit
Chloroform (Slightly), DMF (Slightly)
pka
4.66±0.10(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
InChI
InChI=1S/C22H22N4O4/c1-3-30-22(28)19-18-12-13-25(15-6-4-14(23)5-7-15)21(27)20(18)26(24-19)16-8-10-17(29-2)11-9-16/h4-11H,3,12-13,23H2,1-2H3
InChIKey
UVAQGQOGOJLALA-UHFFFAOYSA-N
SMILES
C1(=O)N(C2=CC=C(N)C=C2)CCC2C(C(OCC)=O)=NN(C3=CC=C(OC)C=C3)C1=2

Sicherheit

ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Ethyl 6-?(4-?Aminophenyl)?-?1-?(4-methoxyphenyl)?-?7-?oxo-?4,?5,?6,?7-?tetrahydro-?1H-?pyrazolo[3,?4-?c]?pyridine-?3-?carboxylate is an impurity of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.

ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 181)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Jinan Jianfeng Chemical Co., Ltd
0531-88110457; +8615562555968
 info@pharmachemm.com China 251 58
Jinan Million Pharmaceutical Co., Ltd
0531-68659554 +8613031714605
 info@millionpharm.com China 252 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497
sales01@cooperate-pharm.com CHINA 1803 55
Hangzhou FandaChem Co.,Ltd. 		+8615858145714
 FandaChem@Gmail.com China 9087 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32957 60
Speranza Chemical Co., Ltd. 		+86-86-075521030354 +8618688942810
 sophieliu@speranzachem.com China 802 55
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838
chloewu@chicopharm.cn CHINA 340 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29880 58
Jinan Chenghui-Shuangda Chemical Co.,Ltd 		+86-531-58897082
ericqiao@jnchsd.com CHINA 158 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254
linda@hubeijusheng.com CHINA 28172 58
  • ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
  • 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
  • 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 6-(4-aMinophenyl)-4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-7-oxo-, ethyl ester
  • Apixaban interMediate
  • ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate
  • Apixaban Impurity 11 ethyl
  • Apixaban Impurity 81
  • ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-te...
  • Intermediates of apixaban
  • X5909
  • ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-ca
  • TECO-012
  • Apixaban Impurity 4 ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7- tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
  • Apixaban Stage-II impurity
  • 503615-07-4
  • 336759-91-8
  • 503615-07-3
  • 503614-47-3
  • 503615-07-4
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