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7-Hydroxymitragynine

7-Hydroxymitragynine Struktur
174418-82-7
CAS-Nr.
174418-82-7
Englisch Name:
7-Hydroxymitragynine
Synonyma:
7-Hydroxy Mitragynine;7- hydroxy-cap lignan;HYDROXYMITRAGYNINE, 7-;7α-Hydroxy-7H-Mitragynine;HYDROXYMITRAGYNINE, 7-(SH);7-Hydroxymitragynine solution;Mitragynine Hydroxyindolenine;7-Hydroxymitragynine wholesale;7-Hydroxy Mitragynine CAS 174418 82 7;9-Methoxycorynantheidine Hydroxyindolenine
CBNumber:
CB82511915
Summenformel:
C23H30N2O5
Molgewicht:
414.49
MOL-Datei:
174418-82-7.mol

7-Hydroxymitragynine Eigenschaften

Siedepunkt:
567.4±50.0 °C(Predicted)
Dichte
1.29±0.1 g/cm3(Predicted)
Flammpunkt:
2℃
storage temp. 
-20°C Freezer
L?slichkeit
Ethanol: 5 mg/ml; Methanol: 10 mg/ml
Aggregatzustand
A crystalline solid
pka
12.20±0.60(Predicted)
InChIKey
RYENLSMHLCNXJT-XIYIOZPINA-N
SMILES
c1c(OC)c2[C@]3(O)CCN4C[C@@H](CC)[C@@H](/C(/C(=O)OC)=C\OC)C[C@@H]4C3=Nc2cc1 |&1:5,11,14,24,r|
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher F,T
R-S?tze: 11-23/24/25-39/23/24/25
S-S?tze: 16-36/37-45
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  1
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H225 Flüssigkeit und Dampf leicht entzündbar. Entzündbare Flüssigkeiten Kategorie 2 Achtung GHS hazard pictogramssrc="/GHS02.jpg" width="20" height="20" /> P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370 Sch?digt die Organe. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 1 Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" /> P260, P264, P270, P307+P311, P321,P405, P501
Sicherheit
P210 Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P260 Dampf/Aerosol/Nebel nicht einatmen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P311 GIFTINFORMATIONSZENTRUM/Arzt anrufen.

7-Hydroxymitragynine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

7-Hydroxymitragynine is a terpenoid indole alkaloid from the plant Mitragyna speciosa, It is a minor constituent of this plant (Ponglux et al., 1994). 7-Hydroxymitragynine exhibited a higher potency than mitragynine in the guinea-pig ileum test and a high affinity for A-opioid receptors in binding assays (Takayama et al., 2002).

Verwenden

A metabolite of Mitragynine. Along with mitragynine, 7-Hydroxymitragynine is an active alkaloid found in the plant Mitragynine speciosa, commonly known as Kratom. The compound possesses opioid agonistic activity with a potentcy 30- and 17-fold higher than that of mitragynine and morphine, respectively.

synthetische

7-Hydroxymitragynine is produced by oxidation of mitragynine and is a minor constituent (< 0.01% in fresh leaves) found at concentrations of up to 2% in leaf extracts and commercial kratom products; however, it is believed to be the major contributor to the known addictive potential of kratom given its activity as a potent μ-opioid receptor agonist.

7-Hydroxymitragynine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


  • 7-Hydroxy Mitragynine
  • (7α,16E,20β)- 1,2,16,17-Tetradehydro-2,7-dihydro-7-hydroxy-9,17-diMethoxycorynan-16-carboxylic acid Methyl Ester
  • (αE,2S,3S,7aS,12bS)-3-Ethyl-1,2,3,4,6,7,7a,12b-octahydro-7a-hydroxy-8-Methoxy-α-(MethoxyMethylene)indolo[2,3-a]quinolizine-2-acetic Acid Methyl Ester
  • 7α-Hydroxy-7H-Mitragynine
  • 9-Methoxycorynantheidine Hydroxyindolenine
  • Mitragynine Hydroxyindolenine
  • HYDROXYMITRAGYNINE, 7-(SH)
  • 7-Hydroxymitragynine solution
  • 7-Hydroxy Mitragynine (100 μg/mL in 0.1 N Ammonia in Methanol)
  • Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethyl-1,2,3,4,6,7,7a,12b-octahydro-7a-hydroxy-8-methoxy-α-(methoxymethylene)-, methyl ester, (αE,2S,3S,7aS,12bS)-
  • 7-Hydroxy Mitragynine CAS 174418 82 7
  • methyl (E)-2-[(2S,3S,7aS,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate
  • 7- hydroxy-cap lignan
  • HYDROXYMITRAGYNINE, 7-
  • 7-Hydroxymitragynine wholesale
  • 174418-82-7
  • Herb extract
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
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