N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Off-white powder
Allgemeine Beschreibung
A potent, selective, competitive, and high affinity inhibitor of arginase. Shown to inhibit arginase from rat liver (IC
50 = 2 μM) and mouse macrophages (IC
50 = 50 μM). Shown to specifically interact with the manganese-cluster of the enzyme active site. Does not function as a substrate or as an inhibitor for NOS. Hence, nor-NOHA may be a useful tool to study the interplays between arginase and NOS.
Biochem/physiol Actions
Primary Targetarginase from rat liver
N-OMEGA-HYDROXY-NOR-L-ARGININE, DIACETATE SALT Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte