JP-1302 (hydrochloride hydrate) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

JP-1302 is an antagonist of α₂-adrenergic receptors (α₂-ARs) that is selective for α_2C-ARs over α_2A- and α_2B-ARs (K_is = 28, 3,150, and 1,470 nM, respectively). It reduces immobility time in the forced swim test in mice when administered at doses of 1, 3, and 10 μmol/kg. JP-1302 (5 mg/kg) reverses phencyclidine-induced decreases in prepulse inhibition of the acoustic startle response in rats. It dose-dependently reduces haloperidol-induced bradykinesia and catalepsy in mice. JP-1302 (0.3 mg/kg) also increases systolic blood pressure in rats.

JP-1302 (hydrochloride hydrate) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

JP-1302 (hydrochloride hydrate) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Cayman Chemical Company	(800)364-9897	Caymanname@qq.com	CHINA	21570	58

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• JP-1302 (hydrochloride hydrate)