4-Acetamidophenylessigsure
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- CAS-Nr.
- 18699-02-0
- Bezeichnung:
- 4-Acetamidophenylessigsure
- Englisch Name:
- Actarit
- Synonyma:
- Orcl;ms932;Mover;FAM79A;TPRG1L;ACTARIT;Ake him;Aktalin;Mirabegron M9;Protein FAM79A
- CBNumber:
- CB7732469
- Summenformel:
- C10H11NO3
- Molgewicht:
- 193.2
- MOL-Datei:
- 18699-02-0.mol
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4-Acetamidophenylessigsure Eigenschaften
- Schmelzpunkt:
- 173-175°C
- Siedepunkt:
- 449.1±28.0 °C(Predicted)
- Dichte
- 1.288±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- DMSO, Ethanol, Methanol
- Aggregatzustand
- Solid
- pka
- 4.34±0.10(Predicted)
- Farbe
- White to Off-White
- Merck
- 14,133
- CAS Datenbank
- 18699-02-0(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| RTECS-Nr. |
CY1542000 |
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| HS Code |
29163990 |
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| Toxizit?t |
LD50 in male, female mice, male, female rats (mg/kg): 1.06, 1.30, 1.95, 2.03 i.p.; 5.68, 5.48, 5.48, 6.12 s.c.; 15.3, 14.7, 14.8, 15.4 orally (Toshida) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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4-Acetamidophenylessigsure Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Actarit is an orally administered disease-modifying antirheumatic drug launched in
Japan. Although its structure resembles that of non-steroidal anti-inflammatory
drugs, it has no effect on experimental acute inflammation and has no analgesic or
antipyretic effects. Its preventative and therapeutic effects on adjuvant arthritis are
mediated via modulation of production and serum level of interleukin-2 which
enhances production of suppressor T-cells to the immune system, thereby,
preventing development of articular lesions.
Chemische Eigenschaften
Crystalline Solid
Verwenden
Antiarthritic
l?uterung methode
Crystallise the acid from MeOH/Me2CO, aqueous EtOH or H2O. The amide has m 231o (from 50% aqueous EtOH). [Gabriel Chem Ber 15 841 1882, Cerecedo et al. J Biol Chem 42 238 1924, Tramontano et al. J Am Chem Soc 110 2282 1988, Beilstein 14 II 281.]
4-Acetamidophenylessigsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Acetamidophenylessigsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 198)Lieferanten
18699-02-0(4-Acetamidophenylessigsure)Verwandte Suche:
- 4-(acetylamino)-benzeneacetic acid
- [4-(ACETYLAMINO)PHENYL]ACETIC ACID
- (p-acetamidophenyl)-aceticaci
- (p-acetamidophenyl)aceticacid
- 4-(acetylamino)-benzeneaceticaci
- 4-n-acetylaminophenylaceticacid
- ms932
- RARECHEM AL BO 1520
- 4-ACETAMIDO-PHENYLACETIC ACID
- ACTARIT
- Mover
- Orcl
- ANTI-TPRGL (N-TERM) antibody produced in rabbit
- FAM79A
- Mossy fiber terminal-associated vertebrate-specific presynaptic protein
- Protein FAM79A
- TPRG1L
- Tumor protein p63-regulated gene 1-like protein
- Mirabegron M9 (YM-340790)
- 4-Acetamido-phenylacetic acid ,97%
- O-(Carboxymethyl)paracetamol
- p-Acetylaminophenylacetic acid
- N-acetyl-4-aMinophenyl-acetic acid
- ActaritIn-houseStandard
- AKETALI (ACTARIT)
- Mirabegron M9
- Benzeneaceticacid, 4-(acetylamino)-
- 2-(4-acetamidocyclohexyl)acetate
- Actarit USP/EP/BP
- Mirabegron-metabolite M9
- Ake him
- 2-(4-acetamidophenyl)aceticaci
- Aktalin
- 18699-02-0
- Aromatic Phenylacetic Acids and Derivatives
- Aromatics
- Intermediates & Fine Chemicals
- Pharmaceuticals
