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SNC 80

SNC 80 Struktur
156727-74-1
CAS-Nr.
156727-74-1
Englisch Name:
SNC 80
Synonyma:
SNC 80;NIH 10815;(+)-4-[(Ar)-alpha-((2s,5r)-4-allyl-2,5-dimethyl-1-piperazinyl)-3;4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-N,N-diethylbenzamide;(+)-4-[(AR)-A-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAM;(+)-4-[(aR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide;(+)-4-[(AR)-A-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAMIDE;(+)-4-[(αr)-α-((2s,5r)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-n,n-diethylbenzamide;(+)-4-[(AR)-ALPHA-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAMIDE;(+)-4-[(alphaR)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide
CBNumber:
CB7712786
Summenformel:
C28H39N3O2
Molgewicht:
449.63
MOL-Datei:
156727-74-1.mol

SNC 80 Eigenschaften

Schmelzpunkt:
122-123°C
Siedepunkt:
564.8±50.0 °C(Predicted)
Dichte
1.040
storage temp. 
Store at RT
L?slichkeit
DMSO: soluble
Aggregatzustand
solid
pka
7.29±0.10(Predicted)
Farbe
off-white
Stabilit?t:
Store in Freezer
InChIKey
KQWVAUSXZDRQPZ-UMTXDNHDSA-N
SMILES
C(N(CC)CC)(=O)C1=CC=C([C@@H](N2C[C@@H](C)N(CC=C)C[C@@H]2C)C2=CC=CC(OC)=C2)C=C1

Sicherheit

WGK Germany  3

SNC 80 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

SNC 80 is a selective nonpeptide agonist of the δ-opioid receptor (Ki = 0.18 nM, IC50 = 2.73 nM) that is over 2,000-fold less effective at the μ-opioid receptor. It effectively activates μ/δ receptor heteromers (EC50 = 52.8 nM) but not κ/δ or μ/κ heteromers. SNC 80 has antinociceptive as well as pro-convulsant effects in vivo.

Chemische Eigenschaften

Crystalline Solid

Verwenden

A highly selective and potent non-peptide -agonist, 2000-fold selective over u-receptors

Biologische Aktivit?t

A highly selective and potent non-peptide δ -opioid agonist, 2000-fold selective over μ -opioid receptors.

SNC 80 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

N,N-diethyl-4-forMylbenzaMide 4-(3-METHOXYBENZOYL)BENZOIC ACID rac-4-(3’-Methoxy-α-hydroxybenzyl)-N,N-diethylbenzamide RAC-4-(3'-METHOXY-A-CHLOROBENZYL)-N,N-DIETHYLBENZAMIDE 3-METHOXYPHENYLMAGNESIUM BROMIDE 4-(3'-METHOXYBENZOYL)-N,N-DIETHYLBENZAMIDE 3-METHOXY-4'-METHYLBENZOPHENONE Piperazine, 2,5-dimethyl-1-(2-propenyl)-, (2R,5S)- (9CI) m-Anisoylchlorid 4-Formylbenzoesure Toluol

Downstream Produkte

SNC 80 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 85)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321
 info@finetechnology-ind.com China 9639 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
Finetech Industry Limited 027-87465837 19945049750
 sales@finetechnology-ind.com China 9648 58
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80

156727-74-1()Verwandte Suche:

  • (+)-4-[(alphaR)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide
  • 4-[(R)-[(2S,5R)-2,5-Dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethylbenzamide
  • (+)-4-[(Ar)-alpha-((2s,5r)-4-allyl-2,5-dimethyl-1-piperazinyl)-3
  • NIH 10815
  • (+)-4-[(AR)-A-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAM
  • (+)-4-[(AR)-A-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAMIDE
  • (+)-4-[(AR)-ALPHA-((2S,5R)-4-ALLYL-2,5-DIMETHYL-1-PIPERAZINYL)-3-METHOXYBENZYL]-N,N-DIETHYLBENZAMIDE
  • SNC 80
  • (+)-4-[(αr)-α-((2s,5r)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-n,n-diethylbenzamide
  • 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-N,N-diethylbenzamide
  • (+)-4-[(aR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide
  • Benzamide, 4-[(R)-[(2S,5R)-2,5-dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethyl-
  • 156727-74-1
  • C28H39N3O2
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Chiral Reagents
  • Opioid receptor and opioid-like receptor
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