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RAC 8-HYDROXY EFAVIRENZ

RAC 8-HYDROXY EFAVIRENZ Struktur
205754-33-2
CAS-Nr.
205754-33-2
Englisch Name:
RAC 8-HYDROXY EFAVIRENZ
Synonyma:
8-HydroxyEfavirenz;RAC 8-HYDROXY EFAVIRENZ;Efavirenz Impurity 11(8-Hydroxy Efavirenz);(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one;6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;(S)-6-Chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one;2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz
CBNumber:
CB7501021
Summenformel:
C14H9ClF3NO3
Molgewicht:
331.67
MOL-Datei:
205754-33-2.mol

RAC 8-HYDROXY EFAVIRENZ Eigenschaften

Schmelzpunkt:
144-154°C
Siedepunkt:
373.6±42.0 °C(Predicted)
Dichte
1?+-.0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
Acetonitrile: soluble; DMSO: soluble; Methanol: soluble
Aggregatzustand
A solid
pka
7.18±0.40(Predicted)
Farbe
White to off-white

Sicherheit

RAC 8-HYDROXY EFAVIRENZ Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.

Chemische Eigenschaften

Off-White Solid

Verwenden

A labellebed metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor

RAC 8-HYDROXY EFAVIRENZ Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


RAC 8-HYDROXY EFAVIRENZ Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 34)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Standardpharm Co. Ltd.
86-714-3992388
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TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Guangzhou PI PI Biotech Inc 020-81716320 +86-13602409664
Sales@pipitech.com China 3633 55
Shanghai Devinchem Ltd 027-65318838 13646286950
sales@devinchem.com China 2997 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60
BOC Sciences 16314854226
info@bocsci.com United States 9923 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
lucy@atkchemical.com China 9952 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58

  • RAC 8-HYDROXY EFAVIRENZ
  • 8-HydroxyEfavirenz
  • 6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
  • (4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
  • Efavirenz Impurity 11(8-Hydroxy Efavirenz)
  • 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-
  • 8-Hydroxy EfavirenzQ: What is 8-Hydroxy Efavirenz Q: What is the CAS Number of 8-Hydroxy Efavirenz Q: What is the storage condition of 8-Hydroxy Efavirenz Q: What are the applications of 8-Hydroxy Efavirenz
  • 2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-
  • (S)-6-Chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one
  • 205754-33-2
  • Metabolites
  • Non-nucleoside Reverse Transcriptase
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
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