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ANHYDROTETRACYCLINE HYDROCHLORIDE

ANHYDROTETRACYCLINE HYDROCHLORIDE Struktur
13803-65-1
CAS-Nr.
13803-65-1
Englisch Name:
ANHYDROTETRACYCLINE HYDROCHLORIDE
Synonyma:
AnhydrotetracyclineHCl;Tetracycline Anhydro HCl;Aureomycin EP impurity J;Anhydrotetracycline HCl, EvoPure;ANHYDROTETRACYCLINE HYDROCHLORIDE;5A,6-ANHYDROTETRACYCLINEHYDROCHLORIDE;Anhydrotetracycline hydrochloride CRS;Anhydrotetracycline hydrochloride ,97%;C10258000 AnhydrotetracyclinEHydrochloride;ANHYDROTETRACYCLINE HYDROCHLORIDE USP/EP/BP
CBNumber:
CB7438626
Summenformel:
C22H23ClN2O7
Molgewicht:
462.88
MOL-Datei:
13803-65-1.mol

ANHYDROTETRACYCLINE HYDROCHLORIDE Eigenschaften

Schmelzpunkt:
223 °C
RTECS-Nr.
QI7860000
storage temp. 
Refrigerator
L?slichkeit
Soluble in ethanol, DMSO, or DMF
Aggregatzustand
Powder
Farbe
Yellow to bright yellow
Sensitive 
Moisture Sensitive
BRN 
4228856
Stabilit?t:
Hygroscopic
EPA chemische Informationen
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4S,4aS,12aS)- (13803-65-1)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 63-36
S-S?tze: 36/37/39-26
WGK Germany  3
HS Code  29413020
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H361 Kann vermutlich die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. Reproduktionstoxizit?t Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P403 An einem gut belüfteten Ort aufbewahren.

ANHYDROTETRACYCLINE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R63:Kann das Kind im Mutterleib m?glicherweise sch?digen.
R36:Reizt die Augen.

S-S?tze Betriebsanweisung:

S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to bind tetO and block transcription. Anhydrotetracycline (hydrochloride) is a powerful effector in both the tetracycline repressor (TetR) and reverse TetR (revTetR) systems, binding the Tet repressor 35-fold more strongly than Tet. Moreover, anhydrotetracycline poorly binds the 30S ribosomal subunit, compared to Tet, so it does not act as a general inhibitor of translation and is a poor antibiotic. Perhaps related to this, the concentration of anhydrotetracycline that inhibits eukaryotic cell growth is more than a 1,000-fold above the dose that alters transcription through TetR.

Chemische Eigenschaften

yellow to bright yellow powder

Verwenden

Anhydrotetracycline hydrochloride is a salt of a degradation product of tetracycline, formed by dehydration at the C6 position under acidic conditions to aromatise the B ring. Anhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, anhydrotetracycline is considered biologically active and is thought responsible for aspects of tetracycline toxicity.

ANHYDROTETRACYCLINE HYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANHYDROTETRACYCLINE HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 113)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5906 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30239 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22784 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19741 58
sgtlifesciences pvt ltd
+8617013299288
dj@sgtlifesciences.com China 12373 58
VladaChem GmbH
+49-7246-3082843
info@vladachem.de Germany 1859 58
Shandong Zhishang New Material Co., Ltd.
+8617653113209
sales002@sdzschem.com China 3049 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490
info@gihichemicals.com China 49978 58

13803-65-1()Verwandte Suche:


  • ANHYDROTETRACYCLINE HYDROCHLORIDE
  • AnhydrotetracyclineHCl
  • Anhydrotetracycline hydrochloride, 'can be used as a secondary standard'
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, monohydrochloride, (4S,4aS,12aS)-
  • 5A,6-ANHYDROTETRACYCLINEHYDROCHLORIDE
  • Anhydrotetracycline hydrochloride,'can be used as secondary standard.'
  • Anhydrotetracycline hydrochloride ,97%
  • (4S,4AS,12AS)-4-(DIMETHYLAMINO)-1,4,4A,5,12,12A-HEXAHYDRO-3,10,11,12A-TETRAHYDROXY-6-METHYL-1,12-DIOXO-2-NAPHTHACENECARBOXAMIDE MONOHYDROCHLORIDE
  • (4S,4aS,12aS)-4-(DiMethylaMino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-Methyl-1,12-dioxo-2-naphthacenecarboxaMide Hydrochloride
  • Lymecycline Impurity 3(Lymecycline EP Impurity C)
  • Anhydrotetracycline hydrochloride CRS
  • Tetracycline Anhydro HCl
  • Aureomycin EP impurity J
  • ANHYDROTETRACYCLINE HYDROCHLORIDE USP/EP/BP
  • Anhydrotetracycline HydrochlorideQ: What is Anhydrotetracycline Hydrochloride Q: What is the CAS Number of Anhydrotetracycline Hydrochloride Q: What is the storage condition of Anhydrotetracycline Hydrochloride Q: What are the applications of Anhydrotetracycline Hydrochloride
  • Anhydrotetracycline Hydrochloride ((4S ,4aS ,12aS )-4-(Dimethylamino)-3,10,11,12a-tetrahydroxy-6-me (1035708)
  • (4S,4aS,12aS)-4-(dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide (anhydrotetracycline)
  • Chlortetracycline Hydrochloride EP Impurity J as Hydrochloride
  • Tetracycline Hydrochloride EP Impurity C as Hydrochloride
  • 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-,hydrochloride (1:1), (4S,4aS,12aS)-
  • Anhydrotetracycline HCl, EvoPure
  • Anhydrotetracycline hydrochloride in methanol
  • C10258000 AnhydrotetracyclinEHydrochloride
  • 13803-65-1
  • Drug Analogues
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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