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SB 218795

SB 218795 Struktur
174635-53-1
CAS-Nr.
174635-53-1
Englisch Name:
SB 218795
Synonyma:
SB 218795;Sb 218795r;Methyl (R)-2-phenyl-2-(2-phenylquinoline-4-carboxamido)acetate;methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate;(-)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide;(-)-(R)-N-(ALPHA-METHOXYCARBONYLBENZYL)-2-PHENYLQUINOLINE-4-CARBOXAMIDE;(R)-[[(2-PHENYL-4-QUINOLINYL)CARBONYL]AMINO]-METHYL ESTER BENZENEACETIC ACID;Benzeneacetic acid, α-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-, methyl ester, (αR)-;Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphar)-;constriction,SB-218795,Neurokinin Receptor,Inhibitor,neurokinin-3,NK receptor,pupillary,inhibit,Tachykinin receptor,SB218795,SB 218795,NK-3
CBNumber:
CB7376630
Summenformel:
C25H20N2O3
Molgewicht:
396.44
MOL-Datei:
174635-53-1.mol

SB 218795 Eigenschaften

Siedepunkt:
623.7±55.0 °C(Predicted)
Dichte
1.237±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO: 40 mg/mL, soluble
Aggregatzustand
solid
pka
11.41±0.46(Predicted)
Farbe
white

Sicherheit

WGK Germany  3

SB 218795 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

SB 218795 is an NK3 receptor antagonist.

Biologische Aktivit?t

Potent, selective and competitive non-peptide NK 3 receptor antagonist (K i = 13 nM at hNK 3 ). Displays 90-fold and 7000-fold selectivity over hNK 2 and hNK 1 receptors respectively. Active in vivo , inhibiting agonist-induced pupillary constriction.

SB 218795 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

SB 218795 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 34)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611
China 9891 58
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
 klq@cw-bio.com China 5926 55
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136
 Sales@ATKchemical.com China 7298 58
Shanghai Han-Xiang Chemical Co., Ltd. 15971444841
 amber@biochempartner.com China 3061 58

174635-53-1()Verwandte Suche:

  • SB 218795
  • (-)-(R)-N-(ALPHA-METHOXYCARBONYLBENZYL)-2-PHENYLQUINOLINE-4-CARBOXAMIDE
  • (R)-[[(2-PHENYL-4-QUINOLINYL)CARBONYL]AMINO]-METHYL ESTER BENZENEACETIC ACID
  • (-)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide
  • Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphar)-
  • Sb 218795r
  • methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate
  • constriction,SB-218795,Neurokinin Receptor,Inhibitor,neurokinin-3,NK receptor,pupillary,inhibit,Tachykinin receptor,SB218795,SB 218795,NK-3
  • Benzeneacetic acid, α-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-, methyl ester, (αR)-
  • Methyl (R)-2-phenyl-2-(2-phenylquinoline-4-carboxamido)acetate
  • 174635-53-1
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