2,5-Dihydroxy-3-undecyl-p-benzochinon
|
|
|
- CAS-Nr.
- 550-24-3
- Bezeichnung:
- 2,5-Dihydroxy-3-undecyl-p-benzochinon
- Englisch Name:
- EMBELIN
- Synonyma:
- EMBELIN;emberine;NSC 91874;Embelin-RM;embelicacid;Embelin, >98%;XIAP INHIBITOR;EMbeliaquinone;TIMTEC-BB SBB005949;Embelin (Embelic acid)
- CBNumber:
- CB7365074
- Summenformel:
- C17H26O4
- Molgewicht:
- 294.39
- MOL-Datei:
- 550-24-3.mol
|
2,5-Dihydroxy-3-undecyl-p-benzochinon Eigenschaften
- Schmelzpunkt:
- 142-143°C
- Siedepunkt:
- 356.15°C (rough estimate)
- Dichte
- 1.131
- Brechungsindex
- 1.4230 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- L?slichkeit
- DMSO: >10 mg/mL
- Aggregatzustand
- solid
- pka
- 2.84±0.50(Predicted)
- Farbe
- Dark orange
- Sensitive
- Light Sensitive
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
- LogP
- 5.024 (est)
Sicherheit
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
DK4230000 |
|
|
2,5-Dihydroxy-3-undecyl-p-benzochinon Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Orange Solid
Definition
ChEBI: A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, an
ineoplastic and inhibitory activity towards hepatitis C protease.
Biologische Aktivit?t
Cell-permeable, non-peptide inhibitor of X-linked inhibitor of apoptosis (XIAP) (IC 50 = 4.1 μ M in competition binding assay with Smac peptide); binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Inhibits cell growth, induces apoptosis and activates caspase-9 in prostate cancer cells (IC 50 4-6 μ M), but has a weaker effect on normal prostate cells (IC 50 = 19-20 μ M). Overcomes the protective effect of XIAP on apoptosis in XIAP-transfected Jurkat cells. Anti-tumor, analgesic and anti-inflammatory in vivo .
2,5-Dihydroxy-3-undecyl-p-benzochinon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,5-Dihydroxy-3-undecyl-p-benzochinon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 194)Lieferanten
550-24-3(2,5-Dihydroxy-3-undecyl-p-benzochinon)Verwandte Suche:
- 2,5-dihydroxy-3-undecyl-p-benzoquinon
- 4-dione,2,5-dihydroxy-3-undecyl-5-cyclohexadiene-1
- embelicacid
- emberine
- APOPTOSIS ACTIVATOR III
- EMBELIN
- 2,5-DIHYDROXY-3-UNDECYL-1,4-BENZOQUINONE
- 2,5-DIHYDROXY-3-UNDECYL-2,5-CYCLOHEXADIENE-1,4-DIONE
- 2,5-DIHYDROXY-3-UNDECYL-P-BENZOQUINONE
- TIMTEC-BB SBB005949
- XIAP INHIBITOR
- embelin from embelia seeds
- 2,5-Cyclohexadiene-1,4-dione, 2,5-dihydroxy-3-undecyl- free base
- EMbeliaquinone
- 2,5-DIHYDROXY-3-UNDECYL-P-BENZOQUINONE, EMBELIN
- 2,5-dihydroxy-3-undecyl-cyclohexa-2,5-diene-1,4-dione
- 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione
- NSC 91874
- Apoptosis Activator III, Embelin
- 2,5-Cyclohexadiene-1,4-dione,2,5-dihydroxy-3-undecyl-
- Embelin, >98%
- Apoptosis Activator III, Embelin - CAS 550-24-3 - Calbiochem
- Embelin (Embelic acid)
- Embelin/Embelic Acid/NSC 91874
- Embelin-RM
- Embelin, cell-permeable inhibitor of X-linked inhibitor of apoptosis
- 550-24-3
- Antibiotics
- Antibiotics A to Z
- Antibiotics A-F
- BioChemical
- Inhibitors
- Anthraquinones, Hydroquinones and Quinones
- Caspases/Apoptosis
