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LOXO-195

LOXO-195 Struktur
1350884-56-8
CAS-Nr.
1350884-56-8
Englisch Name:
LOXO-195
Synonyma:
LOXO-195;LOXO-195(3aR);(6RS)-LOXO-195;LOXO195 R racemic;Selitrectinib Racemate;Selitrectinib(LOXO-195) Racemate;(18bR)-17-Fluoro-1,2,3,11,12,13,14,18b-octahydro-12-methyl-10H-5,7-ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-10-one;12H-15,17-Ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one, 5-fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-, (3aR)-
CBNumber:
CB73311672
Summenformel:
C20H21FN6O
Molgewicht:
380.42
MOL-Datei:
1350884-56-8.mol

LOXO-195 Eigenschaften

Dichte
1.51±0.1 g/cm3(Predicted)
pka
11.44±0.40(Predicted)

Sicherheit

LOXO-195 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

LOXO-195 is an orally available, highly potent, and selective TRK kinase inhibitor designed to overcome drug resistance mediated by acquired mutations. Although responses to TRK inhibition can be dramatic and durable; however, eventually emergence of acquired resistance is found to be inevitable.

LOXO-195 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


LOXO-195 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 46)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29811 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10319 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15352 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203
info@chemextension.com China 42056 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131957 58
Shanghai Changyu Medical Technology Co. Ltd. +86-13301875428
sales@changyuhe.com China 307 58
Shanghai YuanQi Biotechnology Co., Ltd. +86-2332782371 +86-18120098618
sales@adobechem.com China 1250 50

  • LOXO-195
  • LOXO195 R racemic
  • 12H-15,17-Ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one, 5-fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-, (3aR)-
  • Selitrectinib(LOXO-195) Racemate
  • (6RS)-LOXO-195
  • Selitrectinib Racemate
  • (18bR)-17-Fluoro-1,2,3,11,12,13,14,18b-octahydro-12-methyl-10H-5,7-ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-10-one
  • LOXO-195(3aR)
  • 1350884-56-8
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