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AZ9482

AZ9482 Struktur
1825345-33-2
CAS-Nr.
1825345-33-2
Englisch Name:
AZ9482
Synonyma:
AZ9482;AZ 9482;AZ-9482;AZ9482,breast,AZ 9482,inhibit,poly ADP ribose polymerase,PARP,cancer,Inhibitor,AZ-9482;2-(4-(3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)nicotinonitrile;3-Pyridinecarbonitrile, 2-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-
CBNumber:
CB73167318
Summenformel:
C26H22N6O2
Molgewicht:
450.49
MOL-Datei:
1825345-33-2.mol

AZ9482 Eigenschaften

Dichte
1.34±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 0.25mg/mL,DMSO: 0.15mg/mL
Aggregatzustand
A crystalline solid
pka
12.09±0.40(Predicted)
Farbe
White to yellow

Sicherheit

AZ9482 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

AZ9482 is a poly(ADP-ribose) polymerase (PARP) inhibitor (IC50s = 1, 1, 46, 640, 9, and 160 nM for PARP1, -2, -3, -6, TNKS1/PARP5a, and TNKS2, respectively). It induces centrosome declustering (EC50 = <18 nM) and a multipolar spindle phenotype in HeLa cells. AZ9482 inhibits the growth of OCI-LY19 diffuse large B cell lymphoma (DLBCL) cells (GI50 = 3 nM).

AZ9482 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


AZ9482 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 27)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32956 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266
China 4565 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994
2853530910@QQ.com China 8010 62
Shanghai Chaolan Chemical Technology Center 021-QQ:65489617 15618227136
Sales@ATKchemical.com China 7295 58
Twochem Co.Ltd. 021-58111628 15800915896
sales@twochem.com China 1788 58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd. 18081075745
chemflowtech@sina.com China 1886 58
DC Chemicals 021-58447131 13564518121
sales@dcchemicals.com China 9409 58

  • AZ9482
  • AZ 9482;AZ-9482
  • 2-(4-(3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)nicotinonitrile
  • AZ9482,breast,AZ 9482,inhibit,poly ADP ribose polymerase,PARP,cancer,Inhibitor,AZ-9482
  • 3-Pyridinecarbonitrile, 2-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-
  • 1825345-33-2
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