Anti-Leucine-rich α-2-glycoprotein precursor antibody produced in rabbit Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project
(www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these
protocols and other useful information about Prestige Antibodies and the HPA, visit .
Allgemeine Beschreibung
Leucine-rich α-2-glycoprotein 1 (LRG1) was first identified as a trace protein in human serum and it belongs to the leucine-rich repeat (LRR) family. It is involved with various biological processes such as protein-protein interactions, cell signalling and cell adhesion. In presence of transforming growth factor-β1 (TGF-β1), LRG1 shows angiogenesis. It directly binds to the TGF-β accessory receptor endoglin to stimulate the pro-angiogenic Smad1/5/8 signalling pathway. Congenital deficiecny leads to the Bernard-Soulier syndrome.
Anti-Leucine-rich α-2-glycoprotein precursor antibody produced in rabbit Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
