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Anti-Septin-2

Anti-Septin-2 Struktur
CAS-Nr.
Englisch Name:
Anti-Septin-2
Synonyma:
Anti-Septin-2;Protein NEDD5;Anti-Protein NEDD5;Anti-SEPT2 antibody produced in rabbit
CBNumber:
CB72880247
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Anti-Septin-2 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous glycerol solution
Biologische Quelle
rabbit

Sicherheit

Anti-Septin-2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-SEPT2 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

Allgemeine Beschreibung

The gene septin-2 (SEPT2) is mapped to human chromosome 2q37. It belongs to a conserved family of guanosine triphosphate binding proteins required for cell division. SEPT2 is present at the mid-body, the cleavage furrow and the central spindle of cells undergoing cytokinesis. In metaphase cells, SEPT2 is present within the microtubule spindle. SEPT2 is widely expressed with highest levels in brain tissues.

Biochem/physiol Actions

At metaphase septin-2 (SEPT2) is crucial for maintaining CENP-E (Centromere-associated protein E) at kinetochores, required for chromosome congression. In anaphase, SEPT2 is needed for chromosome segregation and spindle elongation. SEPT2 forms a complex with SEPT7 and SEPT9. All three together are present along the length of the axoneme in the primary cilium of retinal pigmented epithelial cells. The complex is crucial for ciliogenesis. SEPT2 is recruited to the site of bacterial entry next to actin and is involved in bacterial invasion of Listeria and Shigella. SEPT2 is up-regulated in human hepatoma carcinoma cells (HCC). Casein kinase-2 mediated phosphorylation of SEPT2 is important for proliferation of HCC.

Anti-Septin-2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Anti-Septin-2 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 11)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Neobioscience Co., Ltd. --
info@neobioscience.com CHINA 6682 58
Shanghai Haoran Biotechnology Co., Ltd. --
470003480@QQ.COM CHINA 6955 58
Beijing Qiangxin Borui Biotechnology Co., Ltd. --
moumou@xxx.com CHINA 2992 58
Shanghai Mengze Biotechnology Co., Ltd. --
luxionggang@126.com CHINA 6393 58
Beijing Bi Orange Blue Biotechnology Co., Ltd. --
bo49855987@163.com CHINA 6827 58
Beijing Shengke Boyuan Biotechnology Co., Ltd. --
978560024@qq.com CHINA 6005 58
Beijing Zhijie Fangyuan Technology Co., Ltd. --
15810200961@163.com CHINA 6984 58
Shanghai Hao Biological Technology Co., Ltd. --
shxiyuanbio@163.com CHINA 6906 58
Shanghai Ziqi Biological Technology Co., Ltd. --
2453006496@qq.com CHINA 6184 58
Guangzhou Dongrui Technology Co., Ltd. --
xiaoshan.wu@dr-tech.com.cn CHINA 2839 58

  • Protein NEDD5
  • Anti-Protein NEDD5
  • Anti-SEPT2 antibody produced in rabbit
  • Anti-Septin-2
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