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KIGAMICIN C

KIGAMICIN C Struktur
680571-51-1
CAS-Nr.
680571-51-1
Englisch Name:
KIGAMICIN C
Synonyma:
KIGAMICIN C;Oxazolo[3,2-b]xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-16,19-dione, 3-[[(2S,5S,6R)-5-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1,2,3,4,8a,9,11,11a,13,14-decahydro-1,4,17,18-tetrahydroxy-11a-methyl-, (1S,3R,4S,8aR,11aR)-
CBNumber:
CB72453298
Summenformel:
C41H47NO16
Molgewicht:
809.81
MOL-Datei:
680571-51-1.mol

KIGAMICIN C Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
Aggregatzustand
Yellow powder.

Sicherheit

KIGAMICIN C Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Kigamicin C was discovered by an anti-austerity strategy, targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blockade of aPKB/Akt activation, caused by the withdrawal of nutrients. It is active in vivo against a human pancreatic cancer xenograft model. Kigamicin C also inhibits the growth of Gram positive bacteria including MRSA, but is not active against Gram negative bacteria.

KIGAMICIN C Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


KIGAMICIN C Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 36)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19741 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
Lynnchem 86-(0)29-85992781 17792393971
info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890
info@novachemistry.com United Kingdom 4381 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
sales@rrkchem.com China 57423 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829
sales@mitachieve.com China 8860 58
Zhejiang Huida Biotech Co., LTD 0571-89903882 13626641628
jiangnan@huidabiotech.com China 3656 58

680571-51-1()Verwandte Suche:


  • KIGAMICIN C
  • Oxazolo[3,2-b]xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-16,19-dione, 3-[[(2S,5S,6R)-5-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1,2,3,4,8a,9,11,11a,13,14-decahydro-1,4,17,18-tetrahydroxy-11a-methyl-, (1S,3R,4S,8aR,11aR)-
  • 680571-51-1
  • C41H47NO16
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