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(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone

(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone Struktur
71801-45-1
CAS-Nr.
71801-45-1
Englisch Name:
(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone
Synonyma:
Ixocarpalactone A;(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone;Ergost-2-en-26-oic acid, 5,6-epoxy-4,16,20,22,23-pentahydroxy-1-oxo-, γ-lactone, (4β,5β,6β,16β,22R,23R,25R)-
CBNumber:
CB72287404
Summenformel:
C28H40O8
Molgewicht:
504.62
MOL-Datei:
71801-45-1.mol

(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone Eigenschaften

Schmelzpunkt:
290-292 °C
Siedepunkt:
741.4±60.0 °C(Predicted)
Dichte
1.36±0.1 g/cm3(Predicted)
pka
13.47±0.70(Predicted)

Sicherheit

(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone Chemische Eigenschaften,Einsatz,Produktion Methoden

Anticancer Research

This terpenoid compound is isolated from the edible plant Physalis philadelphica.The leaf and stem extract induces quinine reductase, a phase II enzyme, needed formetabolism of chemical carcinogens. The anticancer activity of ixocarpalactone isexerted through G2/M phase arrest in cell cycle, downregulation of E2F-1, DP-1,upregulation of hyper-phosphorylated retinoblastoma, and induction of apoptosis inSW480 human colon cancer cells (Balunas and Kinghorn 2005; Choi et al. 2006).

(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 0)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
  • (22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone
  • Ixocarpalactone A
  • Ergost-2-en-26-oic acid, 5,6-epoxy-4,16,20,22,23-pentahydroxy-1-oxo-, γ-lactone, (4β,5β,6β,16β,22R,23R,25R)-
  • 71801-45-1
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