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1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Struktur
85375-15-1
CAS-Nr.
85375-15-1
Englisch Name:
1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
Synonyma:
skf-89976a;SKF89976AHCl;SKF 89976A HYDROCHLORIDE;l-SKF89976A hydrochloride;d,l-SKF89976A hydrochloride;1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE;1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride;1-(4,4-Diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid hydrochloride;Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,d,l-SKF89976A,GABA Receptor,SKF89976A,inhibit,SKF89976A hydrochloride,Inhibitor,SKF-89976A hydrochloride
CBNumber:
CB7194179
Summenformel:
C22H26ClNO2
Molgewicht:
371.9
MOL-Datei:
85375-15-1.mol

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Eigenschaften

storage temp. 
Inert atmosphere,2-8°C
L?slichkeit
DMSO: 20 mg/mL, soluble
Aggregatzustand
solid
Farbe
white

Sicherheit

WGK Germany  3
RTECS-Nr. TM6241000

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

SKF-89976A is a GABA transporters (GATs) type 1 inhibitor.

Biologische Aktivit?t

A potent GABA uptake inhibitor, selective for GAT-1 (IC 50 values are 0.13, 550, 944 and 7210 μ M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (K i = 7 μ M) and transmitter-gated current non-competitively (K i = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo .

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 83)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32956 60
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30238 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894
 shawn@hirisunpharm.com CHINA 9911 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139
 orders@jknbiochem.com China 5221 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Ascent Scientific 4401179829988
customerservice@ascentscientific.co.uk United Kingdom 279 60

85375-15-1()Verwandte Suche:

  • SKF 89976A HYDROCHLORIDE
  • 1-(4,4-DIPHENYL-3-BUTENYL)-3-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE
  • SKF89976AHCl
  • skf-89976a
  • 1-(4,4-Diphenyl-3-buten-1-yl)-3-piperidinecarboxylic acid hydrochloride
  • 1-(4,4-Diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride
  • d,l-SKF89976A hydrochloride
  • l-SKF89976A hydrochloride
  • Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,d,l-SKF89976A,GABA Receptor,SKF89976A,inhibit,SKF89976A hydrochloride,Inhibitor,SKF-89976A hydrochloride
  • 85375-15-1
  • C22H25NO2HCl
  • Ion Channels
  • Ligand-Gated Ion Channels
  • GABA and Glycine Receptor Modulators
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • GABA/Glycine receptor
  • GABA
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