2-(chloromethyl)-4-methylquinazoline
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- CAS-Nr.
- 109113-72-6
- Englisch Name:
- 2-(chloromethyl)-4-methylquinazoline
- Synonyma:
- Quinazoline,2-(chloroMethyl)-4-Methyl-;Linaint-I;Linagliptin INT3;Linagliptin Impurity 67;Linagliptin interMediate A;CHLOROMETHYL)-4-METHYLQUINAZOLINE;2-chloroMethyl-4-Methyl quinaoline;2-(chloromethyl)-4-methylquizoline;Linagliptin 2-Chloromethyl Impurity;2-(chloromethyl)-4-methylquinazolin
- CBNumber:
- CB71648970
- Summenformel:
- C10H9ClN2
- Molgewicht:
- 192.64
- MOL-Datei:
- 109113-72-6.mol
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2-(chloromethyl)-4-methylquinazoline Eigenschaften
- Schmelzpunkt:
- 61.0 to 65.0 °C
- Siedepunkt:
- 240.0±32.0 °C(Predicted)
- Dichte
- 1.251
- Dampfdruck
- 0Pa at 20℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- L?slichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- powder to crystal
- pka
- 1.86±0.50(Predicted)
- Farbe
- Light yellow to Yellow to Orange
- Wasserl?slichkeit
- 3.11g/L at 20℃
- maximale Wellenl?nge (λmax)
- 318nm(EtOH)(lit.)
- InChIKey
- UHCUBOJGMLASBY-UHFFFAOYSA-N
- LogP
- 1.9 at 25℃
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| RIDADR |
3261 |
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| HazardClass |
8 |
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| PackingGroup |
III |
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| HS Code |
2933998090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H314 |
Verursacht schwere Ver?tzungen der Haut und schwere Augensch?den. |
?tzwirkung auf die Haut |
Kategorie 1B |
Achtung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501 |
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| Sicherheit |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P405 |
Unter Verschluss aufbewahren. |
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2-(chloromethyl)-4-methylquinazoline Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White to yellow powder
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 23, p. 1263, 1986
DOI: 10.1002/jhet.5570230458
Synthese
Into a 500ml reaction flask, add o-aminoacetophenone, chloroacetonitrile, 1,4-dioxane, and N-methyl-3(3-sulfopropyl)imidazolium hydrogen sulfate prepared above. Stir to dissolve, cool the reaction system to 8°C, and dropwise add hydrochloric acid to the reaction system. The reaction temperature was kept unchanged during the dropwise addition. After that, the reaction was continued at 8°C for 18 hours to complete the reaction process. After the reaction, ammonia water (the concentration of ammonia water was 10wt%) at 5°C was added to the reaction system. After stirring and crystallizing at 5 for 30 minutes, filter to obtain a filter cake, washing the filter cake with water. Recrystallized with 200ml of dichloromethane to obtain 2-(chloromethyl)-4-methylquinazoline. yield: 85.14%
2-(chloromethyl)-4-methylquinazoline Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-(chloromethyl)-4-methylquinazoline Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 496)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
Shanghai Joiny Pharmaceutical Co.,LTD
|
+8613681955282
|
gyd@joiny-pharma.com |
China |
311 |
58 |
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Hebei Weibang Biotechnology Co., Ltd
|
+8615531157085
|
abby@weibangbio.com |
China |
8810 |
58 |
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Hebei Chuanghai Biotechnology Co,.LTD
|
+86-13131129325
|
sales1@chuanghaibio.com |
China |
5889 |
58 |
|
Anhui Ruihan Technology Co., Ltd
|
+8617756083858
|
daisy@anhuiruihan.com |
China |
973 |
58 |
|
Frapp's ChemicalNFTZ Co., Ltd.
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+86 (576) 8169-6106
|
sales@frappschem.com |
China |
880 |
50 |
|
Capot Chemical Co.,Ltd.
|
+86-（0）57185586718 +86-13336195806
|
sales@capot.com |
China |
29791 |
60 |
|
Shanghai Daken Advanced Materials Co.,Ltd
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+86-371-66670886
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info@dakenam.com |
China |
18751 |
58 |
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Beijing Cooperate Pharmaceutical Co.,Ltd
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010-60279497
|
sales01@cooperate-pharm.com |
CHINA |
1803 |
55 |
|
Henan Tianfu Chemical Co.,Ltd.
|
+86-0371-55170693 +86-19937530512
|
info@tianfuchem.com |
China |
21634 |
55 |
|
Hangzhou FandaChem Co.,Ltd.
|
+8615858145714
|
FandaChem@Gmail.com |
China |
9087 |
55 |
109113-72-6()Verwandte Suche:
- 2-(chloromethyl)-4-methylquinazoline
- Linagliptin interMediate A
- 2-chloroMethyl-4-Methyl quinaoline
- Linagliptin INT3
- Linaint-I
- 2-(chloromethyl)-4-methylquizoline
- Linagliptin 2-Chloromethyl Impurity
- 2-(Chloromethyl)-4-methylquinazoline >
- 2-(chloromethyl)-4-methylquinazolin
- CHLOROMETHYL)-4-METHYLQUINAZOLINE
- 2-(chloromethyl)-4-methylquinazoline ISO 9001：2015 REACH
- (2-(chloromethyl)-4-methylquinazoline)，2-(chloromethyl)-4-methylquinazoline
- Linagliptin intermediates，2-(chloromethyl)-4-methylquinazoline
- Linagliptin Impurity 67
- 2-(chloromethyl)-4-methylquinazolineQ: What is
2-(chloromethyl)-4-methylquinazoline Q: What is the CAS Number of
2-(chloromethyl)-4-methylquinazoline Q: What is the storage condition of
2-(chloromethyl)-4-methylquinazoline
- Quinazoline,2-(chloroMethyl)-4-Methyl-
- Linagliptin Impurity 35(Not Continued,see C4X-110132)
- 2-(Chloromethyl)-4-Methylquinazoline / Linagliptin Intermediate
- Linagliptin intermediate Quinazoline, 2-(chloromethyl)-4-methyl-
- 2-(Chloromethyl)-4-methylquinazoline (2-CMQ)
- 109113-72-6
- 109133-72-6
- Intermediates
- 109113-72-6
