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Z-Leu-Leu-Leu-B(OH)2 (MG262)

Z-Leu-Leu-Leu-B(OH)2 (MG262) Struktur
179324-22-2
CAS-Nr.
179324-22-2
Englisch Name:
Z-Leu-Leu-Leu-B(OH)2 (MG262)
Synonyma:
Z-Leu-Leu-Leu-B(OH)2 (MG262);Proteasome Inhibitor III - Calbiochem;L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1R)-1-borono-3-methylbutyl]-;[(1R)-3-methyl-1-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoyl]amino]butyl]boronic acid
CBNumber:
CB71562203
Summenformel:
C25H42BN3O6
Molgewicht:
491.43
MOL-Datei:
179324-22-2.mol

Z-Leu-Leu-Leu-B(OH)2 (MG262) Eigenschaften

Dichte
1.101±0.06 g/cm3(Predicted)
storage temp. 
-20C
L?slichkeit
≥24.57 mg/mL in DMSO; insoluble in H2O; ≥96.4 mg/mL in EtOH
Aggregatzustand
White solid
pka
9.69±0.43(Predicted)
Farbe
White to off-white

Sicherheit

Z-Leu-Leu-Leu-B(OH)2 (MG262) Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A boronic acid-based, reversible proteasome inhibitor that is structurally similar to MG-132 (Cat. No. 474790) but displays much higher potency (Ki = 0.03 nM versus 4 nM for MG-132).

Biochem/physiol Actions

Target Ki: 30 pM against proteasome

Z-Leu-Leu-Leu-B(OH)2 (MG262) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Z-Leu-Leu-Leu-B(OH)2 (MG262) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 25)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
 order@med-bio.cn China 8140 58
Zhengzhou Akem Chemical Co., Ltd 13303867194
 3001317055@qq.com China 9962 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24644 58
RD International Technology Co., Limited 18024082417
 market@ubiochem.com China 9266 58
ApexBio Technology --
 sales@apexbt.com United States 6251 58
  • Z-Leu-Leu-Leu-B(OH)2 (MG262)
  • [(1R)-3-methyl-1-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoyl]amino]butyl]boronic acid
  • Proteasome Inhibitor III - Calbiochem
  • L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1R)-1-borono-3-methylbutyl]-
  • 179324-22-2
  • C25H42BN3O6
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