BI-2865 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

BI-2865 is a none-covalent pan-KRAS Inhibitor. BI-2865 blocked nucleotide exchange to prevent the activation of wild-type KRAS and a broad range of KRAS mutants, including G12A/C/D/F/V/S, G13C/D, V14I, L19F, Q22K, D33E, Q61H, K117N and A146V/T. Inhibition of downstream signaling and proliferation was restricted to cancer cells harboring mutant KRAS, and drug treatment suppressed KRAS mutant tumor growth in mice without having a detrimental effect on animal weight.

BI-2865 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

BI-2865 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12649	58
TargetMol Chemicals Inc.	+17819995354	marketing@targetmol.com	United States	32297	58
Hubei Chuchang Biotech Co., Ltd.	+undefined15623860702	info@chuchangbiotech.com	China	202	58
Hubei Chuchang Chemical Co., Ltd	18 15623560702	info@chuchangbiotech.com	China	162	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	5619	58
Changzhou Borl Biotechnology Co.,LTD	13606124132;13656121842	luyan0021@163.com	China	221	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	12952	65
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185 18149758185	sales-cpd@caerulumpharma.com	China	3478	58
Shanghai Pansopharm Technology Co., Ltd.	021-20962833 15316628753	sales@pansopharm.com	China	673	60
Hangzhou J&H Chemical Co., Ltd.	0571-+86-571-87396432	sales@jhechem.com	China	15157	59

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• BI-2865
• BI-2865, 10 mM in DMSO
• (S)-2-Amino-4-methyl-4-[3-[4-[(S)-1-[(S)-1-methyl-2-pyrrolidinyl]ethoxy]-2-pyrimidinyl]-1,2,4-oxadiazol-5-yl]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile
• BI-2865 試劑
• 2937327-93-8