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Fananserin

Fananserin Struktur
127625-29-0
CAS-Nr.
127625-29-0
Englisch Name:
Fananserin
Synonyma:
RP-62203;Fananserin;2-[3-[4-(4-Fluorophenyl)piperazino]propyl]-2H-naphth[1,8-cd]isothiazole 1,1-dioxide;2-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide;2-[3-[4-(4-Fluorophenyl)-1-piperazinyl]propyl]-2H-naphthyl[1,8-cd]isothiazole-1,1-dioxide;2H-Naphth[1,8-cd]isothiazole, 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-, 1,1-dioxide;Fananserin,Inhibitor,5-HT Receptor,inhibit,5-HT2,RP62203,RP-62203,dopamine,Dopamine Receptor,Serotonin Receptor,5-hydroxytryptamine Receptor
CBNumber:
CB71073778
Summenformel:
C23H24FN3O2S
Molgewicht:
425.52
MOL-Datei:
127625-29-0.mol

Fananserin Eigenschaften

Schmelzpunkt:
95-97 °C(Solv: acetonitrile (75-05-8))
Siedepunkt:
641.1±65.0 °C(Predicted)
Dichte
1.331±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
L?slichkeit
Soluble to 100 mM in DMSO
Aggregatzustand
Powder
pka
7.31±0.10(Predicted)

Sicherheit

Fananserin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Fananserin is an antagonist of 5-HT2A.

Biologische Aktivit?t

5-HT 2A receptor antagonist that also displays high affinity at D 4 receptors (K i values are 0.26, 2.93, 25, 38, 70 and 726 nM for 5-HT 2A , D 4 , H 1 , α 1 , 5-HT 1A and D 2 receptors respectively). Inhibits inositol phosphate formation evoked by 5-HT in vitro (IC 50 = 7.76 nM) and antagonizes mescaline-induced head twitches in vivo .

Fananserin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Fananserin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 42)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43340 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203
 info@chemextension.com China 42056 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136
 Sales@ATKchemical.com China 7298 58
Aikon International Limited 025-66113011 13155353615
 qzhang@aikonchem.com China 15394 58
Changzhou Chenhong Biotechnology Co., Ltd. 0519-85788828 13775037613
 sales@chemrenpharm.com China 3600 58

127625-29-0()Verwandte Suche:

  • 2-[3-[4-(4-Fluorophenyl)piperazino]propyl]-2H-naphth[1,8-cd]isothiazole 1,1-dioxide
  • RP-62203
  • 2-[3-[4-(4-Fluorophenyl)-1-piperazinyl]propyl]-2H-naphthyl[1,8-cd]isothiazole-1,1-dioxide
  • Fananserin
  • 2H-Naphth[1,8-cd]isothiazole, 2-[3-[4-(4-fluorophenyl)-1-piperazinyl]propyl]-, 1,1-dioxide
  • 2-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide
  • Fananserin,Inhibitor,5-HT Receptor,inhibit,5-HT2,RP62203,RP-62203,dopamine,Dopamine Receptor,Serotonin Receptor,5-hydroxytryptamine Receptor
  • 127625-29-0
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