天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Benzamide, 2-(6-azaspiro[2.5]oct-6-yl)-N-[2-(4,4-difluoro-1-piperidinyl)-6-methyl-4-pyrimidinyl]-4-[[(2-hydroxyethyl)sulfonyl]amino]-

Benzamide, 2-(6-azaspiro[2.5]oct-6-yl)-N-[2-(4,4-difluoro-1-piperidinyl)-6-methyl-4-pyrimidinyl]-4-[[(2-hydroxyethyl)sulfonyl]amino]- Struktur
2410796-79-9
CAS-Nr.
2410796-79-9
Englisch Name:
Benzamide, 2-(6-azaspiro[2.5]oct-6-yl)-N-[2-(4,4-difluoro-1-piperidinyl)-6-methyl-4-pyrimidinyl]-4-[[(2-hydroxyethyl)sulfonyl]amino]-
Synonyma:
AMG-650;AMG 650（Sovilnesib）;Sovilnesib;Sovilnesibum;Sovilnesib(AMG-650);Sovilnesib (Synonyms: AMG 650);Sovilnesib,AMG650,Inhibitor,inhibit,AMG 650,AMG-650,Microtubule/Tubulin;N-[2-(4,4-Difluoro-1-piperidyl)-6-methyl-4-pyrimidinyl]-4-(2-hydroxyethylsulfonamido)-2-(6-azaspiro[2.5]octan-6-yl)benzamide;N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-4-((2-hydroxyethyl)sulfonamido)-2-(6-azaspiro[2.5]octan-6-yl)benzamide;Benzamide, 2-(6-azaspiro[2.5]oct-6-yl)-N-[2-(4,4-difluoro-1-piperidinyl)-6-methyl-4-pyrimidinyl]-4-[[(2-hydroxyethyl)sulfonyl]amino]-
CBNumber:
CB69768453
Summenformel:
C26H34F2N6O4S
Molgewicht:
564.65
MOL-Datei:
2410796-79-9.mol

Benzamide, 2-(6-azaspiro[2.5]oct-6-yl)-N-[2-(4,4-difluoro-1-piperidinyl)-6-methyl-4-pyrimidinyl]-4-[[(2-hydroxyethyl)sulfonyl]amino]- Eigenschaften

Dichte
1.45±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
7.48±0.10(Predicted)
Aggregatzustand
Solid
Farbe
White to off-white
InChIKey
KBDGEJDIHZDPHN-UHFFFAOYSA-N
SMILES
C(NC1C=C(C)N=C(N2CCC(F)(F)CC2)N=1)(=O)C1=CC=C(NS(CCO)(=O)=O)C=C1N1CCC2(CC2)CC1

Sicherheit

Benzamide, 2-(6-azaspiro[2.5]oct-6-yl)-N-[2-(4,4-difluoro-1-piperidinyl)-6-methyl-4-pyrimidinyl]-4-[[(2-hydroxyethyl)sulfonyl]amino]- Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Sovilnesib (AMG 650) is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the research of cancer.

in vitro

Sovilnesib is a kinesin-like protein KIF18A inhibitor.

in vivo

Sovilnesib (AMG 650; 10-100 mg/kg; p.o. daily, for 45 d; female nude mice without thymus with OVCAR-3 xenografts) inhibits tumor growth, Lasting tumor regression and cure occurred in 50% of the animals, Sovilnesib has no apparent toxicity.

Benzamide, 2-(6-azaspiro[2.5]oct-6-yl)-N-[2-(4,4-difluoro-1-piperidinyl)-6-methyl-4-pyrimidinyl]-4-[[(2-hydroxyethyl)sulfonyl]amino]- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Benzamide, 2-(6-azaspiro[2.5]oct-6-yl)-N-[2-(4,4-difluoro-1-piperidinyl)-6-methyl-4-pyrimidinyl]-4-[[(2-hydroxyethyl)sulfonyl]amino]- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 39)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
 sales@chemhifuture.com China 3135 58
Zhejiang Brunova Technology Co., Ltd.
8617857108485 17857108485
 info@zjbrunova.com China 46 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32957 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658
 sales1@artkmedchem.com China 39004 58
Zhejiang Brunova Technology Co., Ltd. 13735468882 17857108485
 info@zjbrunova.com China 69 58
Energy Chemical 021-021-58432009 400-005-6266
 sales8178@energy-chemical.com China 44688 61
NOTA Chemical (Shanghai) Co.,Ltd 021-50189163
sales@notachem.com China 199 64
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185
 sales-cpd@caerulumpharma.com China 3466 58
  • Benzamide, 2-(6-azaspiro[2.5]oct-6-yl)-N-[2-(4,4-difluoro-1-piperidinyl)-6-methyl-4-pyrimidinyl]-4-[[(2-hydroxyethyl)sulfonyl]amino]-
  • Sovilnesib (Synonyms: AMG 650)
  • Sovilnesib
  • AMG 650（Sovilnesib）
  • AMG-650
  • Sovilnesib,AMG650,Inhibitor,inhibit,AMG 650,AMG-650,Microtubule/Tubulin
  • Sovilnesib(AMG-650)
  • N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-4-((2-hydroxyethyl)sulfonamido)-2-(6-azaspiro[2.5]octan-6-yl)benzamide
  • N-[2-(4,4-Difluoro-1-piperidyl)-6-methyl-4-pyrimidinyl]-4-(2-hydroxyethylsulfonamido)-2-(6-azaspiro[2.5]octan-6-yl)benzamide
  • Sovilnesibum
  • 2410796-79-9
  • C26H34F2N6O4S
Copyright 2019 ? ChemicalBook. All rights reserved