ANTI-CASPASE-3 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-Caspase 3, Active antibody has been used:

• for western blotting of cytochrome c for caspase activation
• as primary antibody in immunofluorescence staining of embryos and postnatal mice cryosections
• in Western blot analysis of activated caspase 3
• as a primary antibody in immunodetection of rat brain sections

Allgemeine Beschreibung

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3?is an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases. CASP3?is mapped to human chromosome 4q35.1.

Biochem/physiol Actions

Caspase 3 is one of the key effectors of apoptosis. It acts downstream of caspase 9 in the apoptotic pathway. During apoptosis, it gets activated by proteolytic cleavage into the 17-19 kDa (p17, p18) and 12 kDa (p12) active subunits. Any alteraion in CASP-3 in mice, causes premature lethality. It has also shown that the deletion of gene affects brain development resulting of hyperplasias and disorganized cell deployement. Clinically it is related to Huntington disease (HD). Caspase 3 brings about cell death by activating CAD (caspase activated DNAse I), an endonuclease that causes degradation of chromosomal DNA.

ANTI-CASPASE-3 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-CASPASE-3 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Shanghai Bohu Biotechnology Co., LTD	021-57763112 13585886131	3004987436@qq.com	China	9693	58

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• ANTI-CASPASE-3 (AB-2)
• ANTI-CASPASE-3 (AB-2), HUMAN
• ANTI-CASPASE-3 (AB-2) MOUSE MAB
• ANTI-CASPASE-3 (AB-3)
• ANTI-CASPASE-3 (AB-3), HUMAN
• ANTI-CASPASE-3 (AB-3) MOUSE MAB
• ANTI-CASPASE-3 (AB-4), HUMAN
• ANTI-CASPASE-3 (AB-4) MOUSE MAB
• ANTI-CASP3
• ANTI-CASP3 (AB-1), HUMAN
• ANTI-CASP3 (AB-2), HUMAN
• ANTI-CASP3 (AB-2) MOUSE MAB
• ANTI-CASP3 (AB-3), HUMAN
• ANTI-CASP3 (AB-3) MOUSE MAB
• ANTI-CASP3 (AB-4) MOUSE MAB
• ANTI-CASPASE-3 (HUMAN)
• ANTI-CASPASE-3, HUMAN (RABBIT)
• ANTI-CASPASE-3 RABBIT PAB
• ANTI-CASPASE 3, ACTIVE RABBIT
• ANTI-APOPAIN
• ANTI-APOPAIN (AB-1), HUMAN
• ANTI-APOPAIN (AB-2), HUMAN
• ANTI-APOPAIN (AB-2) MOUSE MAB
• ANTI-APOPAIN (AB-3), HUMAN
• ANTI-APOPAIN (AB-3) MOUSE MAB
• ANTI-APOPAIN (AB-4) MOUSE MAB
• ANTI-APOPAIN, ACTIVE RABBIT
• ANTI-APOPAIN (HUMAN)
• ANTI-APOPAIN, MOUSE
• ANTI-HUMAN CPP32
• ANTI-HUMAN CASPASE-3
• ANTI-ICE-3
• ANTI-ICE-3 (AB-1), HUMAN
• ANTI-ICE-3 (AB-2), HUMAN
• ANTI-ICE-3 (AB-2) MOUSE MAB
• ANTI-ICE-3 (AB-3), HUMAN
• MONOCLONAL ANTIBODY TO CASPASE-3 (HUMAN) (31A1067)
• MONOCLONAL ANTI-CASPASE 3 MOUSE
• Anti-Apopain, Anti-CPP32, Anti-Yama
• Anti-Caspase 3 antibody produced in rabbit
• Anti-Caspase 3, Active antibody produced in rabbit
• Monoclonal Anti-Caspase 3 antibody produced in mouse
• Anti-CASP3 antibody produced in rabbit
• Anti-Caspase-3 precursor
• Anti-Cysteine protease CPP32
• Anti-SREBP cleavage activity 1
• Anti-Yama protein
• Anti-caspase 3, apoptosis-related cysteine peptidase
• Anti-CPP32B
• Anti-SCA1
• Monoclonal Anti-CASP3 antibody produced in mouse
• ANTI-ICE-3 (AB-3) MOUSE MAB
• ANTI-ICE-3 (AB-4) MOUSE MAB
• ANTI-ICE3 (HUMAN)
• ANTI-LICE
• ANTI-LICE (AB-1), HUMAN
• ANTI-LICE (AB-2), HUMAN
• ANTI-LICE (AB-2) MOUSE MAB