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EMEDASTINE FUMARATE

EMEDASTINE FUMARATE Struktur
87233-62-3
CAS-Nr.
87233-62-3
Englisch Name:
EMEDASTINE FUMARATE
Synonyma:
Emadine;1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazoledifumarate;Daren;kb2413;Remicut;kb-2413;kg-2413;AL 3432A;Rapimine;ly188695
CBNumber:
CB6714475
Summenformel:
C25H34N4O9
Molgewicht:
534.56
MOL-Datei:
87233-62-3.mol

EMEDASTINE FUMARATE Eigenschaften

Schmelzpunkt:
148-151°
storage temp. 
2-8°C
L?slichkeit
Soluble in water, sparingly soluble in anhydrous ethanol, very slightly soluble in acetone.
Merck 
14,3557
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
RTECS-Nr. DD8870000
HS Code  2933992600
Toxizit?t LD50 orally in guinea pigs: 744 mg/kg (Fukuda)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

EMEDASTINE FUMARATE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Emedastine difumarate, a potent H1-receptor antagonist, was launched in Japan for the treatment of allergic rhinitis and urticaria. Emedastine exerts its antiallergic effect via inhibition of substance P-induced histamine release. It has been demonstrated both in vitro and in vivo that this effect is mediated by the inhibition of Ca2+release from extracellular stores and of Ca2+ influx into mast cells. In a clinical trial with bronchial asthma, emedastine improved asthmatic symptoms in 55.3% of patients.

Chemische Eigenschaften

White or yellowish powder

Verwenden

Antihistaminic, H1-receptor; asthma prophylactic; anti-allergic.

Definition

ChEBI: The fumaric acid salt of emedastine containing two molecules of fumaric acid for each molecule of emedastine. A relatively selective histamine H1 antagonist, it is used for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.

Hazard

A poison by ingestion.

EMEDASTINE FUMARATE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


EMEDASTINE FUMARATE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 136)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20283 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Hangzhou FandaChem Co.,Ltd.
+8615858145714
FandaChem@Gmail.com China 9087 55
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004
1015@dideu.com China 3942 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-0519-85551759 +8613506123987
marketing1@neostarunited.com China 8838 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30238 58
Dorne Chemical Technology co. LTD
+86-86-13583358881 +8618560316533
Ethan@dornechem.com China 3096 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15352 58
Baoji Guokang Bio-Technology Co., Ltd.
0917-3909592 13892490616
gksales1@gk-bio.com China 9312 58

  • 1-(2-ethoxyethyl)-2-(4-methylhexahydro-1h-1,4-diazepin-1-yl)-benzimidazol
  • 1-(2-ethoxyethyl)-2-(4-methylhexahydro-1h-1,4-diazepin-1-yl)benzimidazolefum
  • 1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepine-1-yl)-1H-benzimidazole·bisfumaric acid
  • Daren
  • Emedastin difumarate
  • Emedastin fumarate
  • Remicut
  • Emedastine Difumarate (100 mg)
  • Rapimine
  • AL 3432A
  • 1-(2-Ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-1H-benzimidazole (2E)-2-butenedioate (1:2)
  • 1h-benzimidazole,1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1h-1,4-diazepin-1-yl)
  • arate(1:2)
  • emedastinedifumarate
  • kb2413
  • kb-2413
  • kg-2413
  • ly188695
  • EMEDASTINE FUMARATE
  • 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole difumarate
  • EmedastineDifumarate>
  • Emedastine difumarate CRS
  • 1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepin-1- yl)-1H-benzimidazole bis[hydrogen (2E)-butenedioate
  • Emestine Fumarate
  • Emedastine Difumarate (1234806)
  • 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazoledifumarate
  • Emadine
  • Fmedastine Difumarate
  • 87233-62-3
  • C25H34N4O9
  • C17H26N4O2C4H4O4
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