(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid
|
|
|
- CAS-Nr.
- 94050-90-5
- Englisch Name:
- (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid
- Synonyma:
- D-HPPA;(R)-2-(4-HYDROXYPHENOXY)PROPIONIC ACID;(R)-(+)-2-(4-Hydroxy;Hydroxy phenyl propionate;Phenyl Acetate Impurity 24;HYDROXYPHENOXYPROPIONIC ACID;(R)-(+)-2-(4-Hydroxyphenoxy);(-)-p-Hydroxyhydratropic acid;(R)-(+)-2-(4-Hydroxyphenoxy)Pr;R-(+)-2-(HYDROXYPHENOXY)PROPIONIC
- CBNumber:
- CB6711601
- Summenformel:
- C9H10O4
- Molgewicht:
- 182.17
- MOL-Datei:
- 94050-90-5.mol
|
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid Eigenschaften
- Schmelzpunkt:
- 145-148 °C (lit.)
- alpha
- 58 º (c=1, MeOH)
- Siedepunkt:
- 367.5±17.0 °C(Predicted)
- Dichte
- 1.302±0.06 g/cm3(Predicted)
- Brechungsindex
- 38 ° (C=0.1, MeOH)
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 3.32±0.10(Predicted)
- Farbe
- Off-White
- Optische Aktivit?t
- [α]20/D +58°, c = 1 in methanol
- InChI
- InChI=1S/C9H10O4/c1-6(9(11)12)13-8-4-2-7(10)3-5-8/h2-6,10H,1H3,(H,11,12)/t6-/m1/s1
- InChIKey
- AQIHDXGKQHFBNW-ZCFIWIBFSA-N
- SMILES
- C(O)(=O)[C@H](OC1=CC=C(O)C=C1)C
- CAS Datenbank
- 94050-90-5(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
|
|
| R-S?tze: |
41 |
|
|
| S-S?tze: |
26-39 |
|
|
| WGK Germany |
1 |
|
|
| HS Code |
29189900 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H318 |
Verursacht schwere Augensch?den. |
Schwere Augensch?digung |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P280, P305+P351+P338, P310 |
|
| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R41:Gefahr ernster Augensch?den.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
White to off-white powder or crystal
Verwenden
(R)-(+)-2-(4-Hydroxyphenoxy)propionic Acid is a degradation product of Cyhalofop-butyl (C989385); an aryloxyphenoxypropionate compound that is used as a herbicide to eliminate grass weeds in rice fields. Cyhalofop-butyl works by selectively inhibiting acetyl CoA carboxylase, an enzyme that is important for the metabolism of fatty acids.
Synthese
(R)-2-(4-hydroxyphenoxy)propionic acid ((R)-HPOPA) is an essential intermediate for the production of chiral aryloxyphenoxypropionic acid-type herbicides such as clod inafop-propargyl, cyhalofop-butyl, fenoxaprop-p-ethyl, metam ifop, quizalofop-p-ethyl, and quizalofop-p-tefuryl. In general, there are three chemical methods for the preparation of (R)-HPOPA: (1) resolution of racemic HPOPA with alkaloids such as quinine, cinchonine, ephedrine, vauquline or chiral agents such as S-(?)-α-phenylethylamine, L-(+)-chloromethane, R-(+)-α-isopropyl-4-chlorobenzylamine and (2) asymmetric synthesis from L-lactic acids or L-alanine. However, these methods are not always useful for industrial applications because of expensive reagents, problems with enantiopurity of product and low yields. Regioselective hydroxylation of (R)-2-phenoxypropionic acid ((R)-POPA) by microbes is a highly feasible method for the production of (R)-HPOPA, which under mild conditions allows complete transformation of substrate into a single stereoisomeric product with a high yield and without byproduct formation[1-2].
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 371)Lieferanten
94050-90-5()Verwandte Suche:
- （R）-（+）-（4-hydroxyphenoxy)-propionic acid
- (2R)-2-(4-hydroxyphenoxy)propanoic acid
- R-(+)-2-(HYDROXYPHENOXY)PROPIONIC
- (R)-(+)-2-(HYDROXYPHENOXY)PROPIONIC ACID
- (R)-2-(4-HYDROPHENOXY)PROPIONIC ACID
- R-2-(4-HYDROXYPHENOXY)PROPANOIC ACID
- (R)-(+)-2-(4-HYDROXYPHENOXY)PROPIONIC ACID
- D-2-(4-HYDROXYPHENOXY)PROPIONIC ACID
- (R)-(+)-2-(4-HYDROXYPENOXY)PROPIONIC ACID
- HYDROXYPHENOXYPROPIONIC ACID
- (R)-(+)-2-(4-Hydroxyphenoxy)Pr
- R-(+)-2-(4-HYDROXYPHENYL)PROPIONIC ACID
- R-2-(4-Hydroxyphenoxy)propanoic aicd
- R-(+)-2-(4-Hydrobenzoxy)propionic acid
- (-)-p-Hydroxyhydratropic acid
- [R,(-)]-2-(p-Hydroxyphenyl)propionic acid
- (S)-2-(4-Hydroxyphenyl)propionic acid
- [S,(+)]-2-(p-Hydroxyphenyl)propionic acid
- (R)-2-(p-Hydroxyphenoxy)propionic acid
- (R)-(+)-2-(4-Hydroxy
- Propanoicacid, 2-(4-hydroxyphenoxy)-, (2R)-
- R - (+) - 2 - (4 - hydroxyl phenoxy) propionic acid
- (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid 98%
- Hydroxy phenyl propionate
- (R) -(+) -2- (4-Hydroxyphenoxy) propanoic acid (D-HPPA)
- (R)-(+)-2-(4-Hydroxyphenoxy)propionicAcid>
- (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid ISO 9001：2015 REACH
- (R)-(+)-2-(4-Hydroxyphenoxy)
- Pesticide Intermediate CAS?94050-90-5?(R) - (+) -2- (4-Hydroxy Phenoxy) Propionic Acid
- (R)-2-(4-HYDROXYPHENOXY)PROPIONIC ACID
- D-HPPA
- (R-(+-2-(4-hydroxyphenoxy)propylene Sour
- Phenyl Acetate Impurity 24
- 94050-90-5
- Carboxylic Acids
- Asymmetric Synthesis
- Chiral Building Blocks
- Organic Building Blocks
- Carboxylic Acids
- Chiral Building Blocks
- Organic Building Blocks
- CHIRAL COMPOUNDS
- Aromatic Propionic Acids
