ANTI-GLUTAMATE DECARBOXYLASE, G65
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- CAS-Nr.
- Englisch Name:
- ANTI-GLUTAMATE DECARBOXYLASE, G65
- Synonyma:
- Anti-GAD2;ANTI-GAD 65;Anti-MGC161605;Anti-MGC161607;ANTI-GAD 65, 5-22;ANTI-GAD 65, 514-530;Anti-Glutamate decarboxylase 2;ANTI-GLUTAMATE DECARBOXYLASE, 65;ANTI-GLUTAMATE DECARBOXYLASE, G65;ANTI-GLUTAMIC ACID DECARBOXYLASE 65
- CBNumber:
- CB6406646
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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ANTI-GLUTAMATE DECARBOXYLASE, G65 Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- buffered aqueous solution
ANTI-GLUTAMATE DECARBOXYLASE, G65 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-Glutamic Acid Decarboxylase 65 antibody produced in rabbit is suitable as a primary antibody for the determination of expression of GAD 65 isoform in putative P boutons in rat and mouse at a working dilution of 1:5000 and in lysates prepared from rat testis at different developmental ages and rat cerebellum by immunoblotting.
It is also suitable for immunohistochemistry at a working dilution of 1:500 using formalin-fixed, paraffin-embedded sections of rat pancreas and for microarray.
Allgemeine Beschreibung
GAD is predominantly expressed in the central nervous system (CNS) and pancreatic islets. It is also expressed in testis, oviduct and ovary. GAD exists in two isofoms, GAD 65 and GAD 67. GAD65 is targeted to membranes and nerve endings.
Biochem/physiol Actions
Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L-glutamate to γ-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. It has been identified as an autoantigen in insulin-dependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS) and may serve as a marker in the early stages of IDDM. GAD 65 synthesizes transmitter GABA for vesicular release.
ANTI-GLUTAMATE DECARBOXYLASE, G65 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ANTI-GLUTAMATE DECARBOXYLASE, G65 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 18)Lieferanten
- ANTI-GLUTAMATE DECARBOXYLASE, 65
- ANTI-GLUTAMATE DECARBOXYLASE B10351, G65
- ANTI-GLUTAMATE DECARBOXYLASE, G65
- ANTI-GLUTAMATE DECARBOXYLASE (GAD65)
- ANTI-GLUTAMIC ACID DECARBOXYLASE 65
- ANTI-GLUTAMIC ACID DECARBOXYLASE 65 (GAD65)
- ANTI-GAD 65
- ANTI-GAD 65, 514-530
- ANTI-GAD 65, 5-22
- Monoclonal Anti-Glutamic Acid Decarboxylase 65 antibody produced in mouse
- Anti-Glutamic Acid Decarboxylase 65 (514-530) antibody produced in rabbit
- Anti-GAD2/GAD65 antibody produced in goat
- Anti-Glutamate decarboxylase 2
- Anti-GAD2 antibody produced in rabbit
- Anti-Glutamate decarboxylase 2 (pancreatic islets and brain, 65kda)
- Anti-GAD2
- Anti-glutamate decarboxylase 65 kDa isoform
- Monoclonal Anti-GAD65 antibody produced in mouse
- Anti-MGC161605
- Anti-MGC161607
- Anti-Glutamic Acid Decarboxylase 65 (5-22) antibody produced in rabbit
