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Aurora Kinase Inhibitor II

Aurora Kinase Inhibitor II Struktur
331770-21-9
CAS-Nr.
331770-21-9
Englisch Name:
Aurora Kinase Inhibitor II
Synonyma:
IUN-70219;Aurora kinase inhibitor-2;Aurora kinase inhibitor-2, 10 mM in DMSO;N-(4-((6,7-Dimethoxyquinazolin-4-yl)amino)phenyl)benzamide;Benzamide, N-[4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenyl]-;inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aurora kinase inhibitor 2,Aurora kinase inhibitor-2,Aurora-B,Inhibitor
CBNumber:
CB63136779
Summenformel:
C23H20N4O3
Molgewicht:
400.43
MOL-Datei:
331770-21-9.mol

Aurora Kinase Inhibitor II Eigenschaften

Siedepunkt:
518.6±50.0 °C(Predicted)
Dichte
1.321±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
L?slichkeit
DMF:0.25(Max Conc. mg/mL);0.62(Max Conc. mM)
DMF:PBS(pH7.2) (1:2):0.33(Max Conc. mg/mL);0.82(Max Conc. mM)
DMSO:2.5(Max Conc. mg/mL);6.2(Max Conc. mM)
Aggregatzustand
A crystalline solid
pka
13.01±0.70(Predicted)
Farbe
White to yellow

Sicherheit

Aurora Kinase Inhibitor II Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC50 = 0.39 μM). In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 μM.

Aurora Kinase Inhibitor II Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Aurora Kinase Inhibitor II Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 33)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+17819995354
 marketing@targetmol.com United States 32292 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38670 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266
 China 4621 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9803 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903
 3008007409@qq.com China 71826 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994
 2853530910@QQ.com China 7990 62
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
 lucy@atkchemical.com China 9994 58
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123
 1014988033@qq.com China 4951 55
  • Aurora kinase inhibitor-2
  • IUN-70219
  • N-(4-((6,7-Dimethoxyquinazolin-4-yl)amino)phenyl)benzamide
  • inhibit,Aurora-A,Aurora kinase inhibitor2,Aurora Kinase,ATP-competitive,Aurora kinase inhibitor 2,Aurora kinase inhibitor-2,Aurora-B,Inhibitor
  • Benzamide, N-[4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenyl]-
  • Aurora kinase inhibitor-2, 10 mM in DMSO
  • 331770-21-9
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