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Lumateperone

Lumateperone Struktur
313368-91-1
CAS-Nr.
313368-91-1
Englisch Name:
Lumateperone
Synonyma:
Lumateperone;ITI-722;Lumepperone;Lumiperidone;Lumateperone ITI-722;ITI-722 lumateperone;Lumateperone, 10 mM in DMSO;313368-91-1Lumateperone(ITI-007);1-(4-fluorophenyl)-4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H-pyrido[3‘,4‘:4,5]pyrrolo[1,2,3-de]quinoxalin-8-yl)butan-1-one;1-(4-Fluorophenyl)-4-[(6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]-1-butanone
CBNumber:
CB63032893
Summenformel:
C24H28FN3O
Molgewicht:
393.5
MOL-Datei:
313368-91-1.mol

Lumateperone Eigenschaften

Siedepunkt:
556.4±50.0 °C(Predicted)
Dichte
1.26±0.1 g/cm3(Predicted)
pka
9.10±0.20(Predicted)
Aggregatzustand
Oil
Farbe
Colorless to light yellow

Sicherheit

Lumateperone Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Lumateperone is a novel antipsychotic agent with a unique mechanism of action with high 5-hydroxytryptamine 2A(5-HT2A) blocking activity. A Phase 2 study in treatment of insomnia revealed strong evidence of efficacy, with no impairment of next-day cognition.

Verwenden

Lumateperone was a drug developed for the treatment of schizophrenia. May have applications in bipolar depression.

Synthese

Synthesis of Lumateperone
Lumateperone synthesis

Lager

Store at 0-8℃

Lumateperone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

4'-Fluor-4-iodbutyrophenon 1H-Pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline, 2,3,6b,7,8,9,10,10a-octahydro-3-methyl- (6bR,10aS)-3-Methyl-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline 4-FLUOROPHENYLMAGNESIUM BROMIDE 4-Chlor-4'-fluorbutyrophenon

Downstream Produkte

Lumateperone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 98)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Chengdu Aupone Pharmaceutical Co.Ltd.
+86-28-+86-28-87843998-6060-6060 +8618631098571
 lijiaqi@aupone.com China 55 58
shandong perfect biotechnology co.ltd 		+86-53169958659 +86-13153181156
 sales@sdperfect.com China 294 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		+8618627948422
 sale@hdimpurity.com China 3662 58
Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479
sales@fine-chemtech.com CHINA 885 55
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19552 58
Shanghai Jinghao Pharmaceutical Co.,Ltd 		+86-21-68900963
sales@jinghaopharma.com CHINA 153 58
TargetMol Chemicals Inc. 		+17819995354
 marketing@targetmol.com United States 32277 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30230 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750
 info@finetechnology-ind.com China 9642 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
  • ITI-722
  • ITI-722 lumateperone
  • 1-(4-fluorophenyl)-4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H-pyrido[3‘,4‘:4,5]pyrrolo[1,2,3-de]quinoxalin-8-yl)butan-1-one
  • 313368-91-1Lumateperone(ITI-007)
  • 1-Butanone, 1-(4-fluorophenyl)-4-[(6bR,10aS)-2,3,6b,9,10,10a-hexahydro-3-methyl-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]-
  • 1-(4-fluorophenyl)-4-((6bR,10aS)-3-methyl-2,3,6b,7,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-8(9H)-yl)butan-1-one
  • 1-(4-Fluorophenyl)-4-[(6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]-1-butanone
  • Lumateperone
  • presynaptic D2 receptor,dopamine D1 receptor,Serotonin Receptor,postsynaptic D2 receptor,Dopamine Receptor,5-HT2A,schizophrenia,ITI 007,Lumateperone,inhibit,Inhibitor,5-HT Receptor,5-hydroxytryptamine Receptor
  • Lumateperone ITI-722
  • Lumepperone
  • Lumateperone, 10 mM in DMSO
  • Lumiperidone
  • 313368-91-1
  • C24H28FN3O
  • API
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