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CAY10650

CAY10650 Struktur
1233706-88-1
CAS-Nr.
1233706-88-1
Englisch Name:
CAY10650
Synonyma:
CS-1520;CAY10650;CAY10650, >=98%;CAY 10650;CAY-10650;CAY10650;CAY-10650;CAY 10650;3-isobutanoyl-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]indole-5-carboxylic acid;3-isobutyryl-1-(2-oxo-3-(4-phenoxyphenoxy)propyl)-1H-indole-5-carboxylic acid;3-(2-methylpropanoyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid;3-(2-Methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid;1H-Indole-5-carboxylic acid, 3-(2-Methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-
CBNumber:
CB62590453
Summenformel:
C28H25NO6
Molgewicht:
471.5
MOL-Datei:
1233706-88-1.mol

CAY10650 Eigenschaften

Schmelzpunkt:
103-104℃
Siedepunkt:
685.4±55.0 °C(Predicted)
Dichte
1.24±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml
pka
4.03±0.30(Predicted)
Aggregatzustand
Powder
Farbe
White to off-white

Sicherheit

CAY10650 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Cytosolic phospholipase A2α (cPLA2α) specifically catalyzes the hydrolysis of arachidonic acid from the sn-2-ester position of membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes, both important mediators of the inflammatory process. CAY10650 is a highly potent (IC50 = 12 nM) cPLA2α inhibitor. It demonstrates strong anti-inflammatory effects when applied topically at a dose of 0.1 mg/ear in a mouse model of acute irritant contact dermatitis. The phase I metabolite of this compound, CAY10641 , is also available.

CAY10650 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CAY10650 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 63)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32957 60
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30238 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Coresyn Pharmatech Co., Ltd. 		+86-571-86626709 +86-18157142896
 cbc@coresyn.com China 9984 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203
 info@chemextension.com China 42056 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Haoyuan Chemexpress Co., Ltd. 021-58950125
info@chemexpress.com China 7552 61
  • CAY10650
  • 1H-Indole-5-carboxylic acid, 3-(2-Methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-
  • 3-(2-Methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid
  • CAY10650, >=98%
  • CAY 10650;CAY-10650
  • CAY10650;CAY-10650;CAY 10650
  • CS-1520
  • 3-isobutanoyl-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]indole-5-carboxylic acid
  • 3-isobutyryl-1-(2-oxo-3-(4-phenoxyphenoxy)propyl)-1H-indole-5-carboxylic acid
  • acanthamoeba,inhibit,CAY 10650,PGE2,CAY10650,lipid droplets,neutrophils,keratitis,mannose-induced protein,corneal epithelial cells,CAY-10650,Inhibitor,Phospholipase
  • 3-(2-methylpropanoyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid
  • 1233706-88-1
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