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1,3-bis(4-Bromophenyl)-5-phenyl-2,4-imidazolidinedione

1,3-bis(4-Bromophenyl)-5-phenyl-2,4-imidazolidinedione Struktur
878533-35-8
CAS-Nr.
878533-35-8
Englisch Name:
1,3-bis(4-Bromophenyl)-5-phenyl-2,4-imidazolidinedione
Synonyma:
CAY10508;1,3-bis(4-Bromophenyl)-5-phenyl-2,4-imidazolidinedione;2,4-Imidazolidinedione, 1,3-bis(4-bromophenyl)-5-phenyl-
CBNumber:
CB62520816
Summenformel:
C21H14Br2N2O2
Molgewicht:
486.16
MOL-Datei:
878533-35-8.mol

1,3-bis(4-Bromophenyl)-5-phenyl-2,4-imidazolidinedione Eigenschaften

L?slichkeit
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:2): .25 mg/ml; DMSO: 10 mg/ml
Aggregatzustand
Solid

Sicherheit

1,3-bis(4-Bromophenyl)-5-phenyl-2,4-imidazolidinedione Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Central cannabinoid (CB1) receptor antagonists and inverse agonists exhibit therapeutic potential for obesity and drug dependence, while being devoid of psychotropic effects. CAY10508 is a potent and selective central cannabinoid (CB1) receptor inverse agonist with a Ki value of 243 nM and an EC50 of 195 nM. A 10 μM concentration of CAY10508 resulted in 100% and 35% displacement of [3H]-CP-55,940 at the CB1 and peripheral cannabinoid (CB2) receptors, respectively. A [35S]-GTPγS binding assay revealed the inverse agonist properties of CAY10508 at the CB1 receptor.

Verwenden

An imidazolidine-2,-4-dione derivative that is an effective and selective inverse agonist of CB cannabinoid receptor

1,3-bis(4-Bromophenyl)-5-phenyl-2,4-imidazolidinedione Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1,3-bis(4-Bromophenyl)-5-phenyl-2,4-imidazolidinedione Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 24)Lieferanten
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  • 1,3-bis(4-Bromophenyl)-5-phenyl-2,4-imidazolidinedione
  • CAY10508
  • 2,4-Imidazolidinedione, 1,3-bis(4-bromophenyl)-5-phenyl-
  • 878533-35-8
  • Cannabinoids.
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