Morphine Sulfate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

Morphine (sulfate hydrate) (Item No. 25955) is an analytical reference standard categorized as an opioid. It is a natural phenanthrene commonly used for its analgesic properties but has a high potential for addiction. Morphine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.

Chemische Eigenschaften

White Solid

Verwenden

Principal alkaloid of opium. This is a controlled substance (opiate). Analgesic (narcotic)

Acquired resistance

The analgesic effect of orally dosed morphine can equal that obtained by parenteral administration, if proper doses are given. When given orally, the initial dose of morphine is usually 60 mg, followed by maintenance doses of 20 to 30 mg every 4 hours. Addiction to clinically used morphine by the oral route generally is not a problem.

Mechanism of action

Morphine sulfate is the analgesic used most often for severe, acute, and chronic pain. Morphine is a μ agonist and is a Schedule II drug. It is available in intramuscular, subcutaneous, oral, rectal, epidural, and intrathecal dosage forms. The epidural and intrathecal preparations are formulated without a preservative.Morphine is three- to six times more potent when given intramuscularly than when given orally. The difference in activity results from extensive first-pass 3-O-glucuronidation of morphine—an inactive metabolite. The half-life of intramuscularly dosed (10 mg) morphine is approximately 3 hours. The dose of morphine, by any dosage route, must be reduced in patients with renal failure and in geriatric and pediatric patients. The enhanced effects of morphine in renal failure is believed to be caused by a buildup of the active 6-glucuronide metabolite, which depends on renal function for elimination.

Morphine Sulfate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

6211-15-0()Verwandte Suche:

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• Astramor ph
• Astramor ph (tn)
• Avinza (tn)
• D00842
• Depodur
• Depodur (tn)
• Kadian (tn)
• Morphine Sulfate CII (500 mg)
• Morphine Sulfate (CII), USP
• Morphine for system suitability
• Morphine sulfat
• Morphine pentahydrate sulfate salt
• 4,5-alpha-epoxy-17-methylmorphinan-3,5-alpha-diolsulfatehydrate(2:1:5)
• 6-diol,7,8-didehydro-4,5-epoxy-17-methyl-(5-alpha,6-alpha)-morphinan-sulfa
• te(2:1)(salt),pentahdrate
• MORPHINE SULFATE
• MORPHINE SULFATE HYDRATE
• MORPHINE SULFATE PENTAHYDRATE
• MORPHINE HEMI[SULFATE PENTAHYDRATE]
• Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5.alpha.,6.alpha.)-, sulfate (2:1) (salt), pentahydrate
• morphine sulfate salt pentahydrate
• MORPHINESULFATE,USP
• 4,5-alpha-epoxy-17-methylmorphinan-3,5-alpha-diol sulfate hydrate
• (5a,6a)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol Sulfate Hydrate
• Aguettant Sulfate Hydrate
• Morphia Sulfate Hydrate
• Morphina Sulfate Hydrate
• Morphine Sulfate Pentahydrate USP
• Nepenthe Sulfate Hydrate
• Ospalivina Sulfate Hydrate
• morphine sulfate--dea schedule ii item
• Morphine Sulfate 20 mg Tablets
• Morphine sulfate - * narc CRS (Y0000452)
• Morphine Hemisulphate Pentahemihydrate
• Apomorphine impurity B (morphine sulfate)
• Morphine Impurity 1
• Apomorphine impurity B (morphine sulfate hydrate)
• Ethylmorphine Hydrochloride Impurity B as Hemisulfate Pentahemihydrate
• Codeine Monohydrate Impurity B as Hemisulphate Pentahemihydrate
• Apomorphine Hydrochloride Hemihydrate EP Impurity B
• 6211-15-0
• C34H50N2O15S
• 2C17H19NO35H2OH2O4S
• C34H40N2O10S5H2O
• 2C17H19NO3H2O4S5H2O
• Pharmaceuticals
• Intermediates & Fine Chemicals