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Sulfathiazol

Sulfathiazole Struktur
72-14-0
CAS-Nr.
72-14-0
Bezeichnung:
Sulfathiazol
Englisch Name:
Sulfathiazole
Synonyma:
ST;NORSULFAZOLE;Sulphathiazole;Norsulfazol;SULFATHIAZOL;Sulfathiazloe;Duatok;Dulana;m&b760;m+b760
CBNumber:
CB6133470
Summenformel:
C9H9N3O2S2
Molgewicht:
255.32
MOL-Datei:
72-14-0.mol

Sulfathiazol Eigenschaften

Schmelzpunkt:
200-202 °C (lit.)
Siedepunkt:
479.5±47.0 °C(Predicted)
Dichte
1.4629 (rough estimate)
Brechungsindex
1.6560 (estimate)
storage temp. 
2-8°C
L?slichkeit
0.5g/l
pka
7.2(at 25℃)
Aggregatzustand
Solid
Farbe
White
Wasserl?slichkeit
Insoluble (<0.1 g/100 mL at 21 ºC)
Merck 
14,8943
BRN 
226178
Stabilit?t:
Stable. Incompatible with strong oxidizing agents.
InChIKey
JNMRHUJNCSQMMB-UHFFFAOYSA-N
CAS Datenbank
72-14-0(CAS DataBase Reference)
NIST chemische Informationen
Sulfathiazole(72-14-0)
EPA chemische Informationen
Sulfathiazole (72-14-0)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-36
RIDADR  3249
WGK Germany  2
RTECS-Nr. WP2360000
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29350090
Giftige Stoffe Daten 72-14-0(Hazardous Substances Data)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
H412 Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 3 P273, P501
Sicherheit
P261 Einatmen von Staub vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P271 Nur im Freien oder in gut belüfteten R?umen verwenden.
P273 Freisetzung in die Umwelt vermeiden.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Sulfathiazol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

white to cream powder

Verwenden

Sulfonamide antibacterial.

Definition

ChEBI: A 1,3-thiazole compound having a 4-aminobenzenesulfonamido group at the 2-position.

Weltgesundheitsorganisation (WHO)

Sulfathiazole, a sulfonamide anti-infective agent, was introduced more than 25 years ago for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing bacterial resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Although preparations remain available, use of the drug has been discontinued in many countries.

Allgemeine Beschreibung

White crystalline powder. Is dimorphous: form I is consists of prismatic rods and form II of six-sided plates and prisms. Insoluble in water and soluble in dil aqueous acid and aqueous base.

Air & Water Reaktionen

May be sensitive to heat, air and light during long-term storage . Insoluble in water.

Reaktivit?t anzeigen

Sulfathiazole is an amino acid.

Brandgefahr

Flash point data for Sulfathiazole are not available, but Sulfathiazole is probably combustible.

Pharmazeutische Anwendungen

2-Sulfanilamidothiazole. A short-acting compound (half-life c. 4 h) with relatively high activity. Protein binding is c. 75%. Its use has declined because of a high incidence of side effects. It is one of the constituents of triple sulfonamide mixtures, of which local preparations are still available.
Two compounds, phthalylsulfathiazole (sulfathalidine) and succinylsulfathiazole (sulfasuxidine) owe their activity to the slow liberation of sulfathiazole in the bowel. They are poorly soluble and very little is absorbed after oral administration. They were formerly used in the treatment of intestinal infections and in bowel preparation before surgery. They are available in multi-ingredient preparations in some countries.

Sicherheitsprofil

Human poison by unspecified route. Experimental poison by intraperitoneal route, Moderately toxic by intravenous, subcutaneous, and parenteral routes. Mildly toxic by ingestion. Human systemic effects by unspecified route: conjunctiva irritation, tubule changes, and allergic skin dermatitis. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data, Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Sulfathiazol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Sulfathiazol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 463)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Xiamen Eagle Chemical Limited Corporation

yiyunchem@163.com China 5850 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8810 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
+8615350851019
admin@86-ss.com China 1001 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +8618949832763
info@tnjchem.com China 2986 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
sales@sdzschem.com China 2930 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5906 58

72-14-0(Sulfathiazol)Verwandte Suche:


  • 4-amino-n-2-thiazolyl-benzenesulfonamid
  • Azoquimiol
  • Azoseptale
  • Benzenesulfonamide, 4-amino-N-2-thiazolyl-
  • Cerazol
  • Cerazol (suspension)
  • cerazol(suspension)
  • Cerazole
  • Chemosept
  • Ciba 3714
  • ciba3714
  • Cibazol
  • Coco-Thiazole
  • Duatok
  • Dulana
  • Eleudron
  • Enterobiocine
  • Estafilol
  • Formosulfathiazole
  • M&B 760
  • m&b760
  • M+B 760
  • m+b760
  • n(1)-2-thiazolyl-sulfanilamid
  • N(Sup1)-(2-Thiazolyl)sulfanilamide
  • n(sup1)-2-thiazolyl-sulfanilamid
  • n(sup1)-2-thiazolylsulfanilamide
  • Neostrepsan
  • Norsulfasol
  • Planomide
  • Poliseptil
  • RP 2090
  • rp2090
  • Sanotiazol
  • Septozol
  • Streptosilthiazole
  • Sulfamul
  • Sulfanilamide, N(sup1)-2-thiazolyl-
  • Sulfanilamide, N1-2-thiazolyl-
  • 2-SULFANILAMIDOTHIAZOLE
  • 2-(SULFANILAMINO)THIAZOLE
  • 2-(4-AMINOBENZENESULFONAMIDO)THIAZOLE
  • 2-(P-AMINOBENZENESULFONAMIDO)THIAZOLE
  • Sulfanilamide, N1-4-thiazolin-2-ylidene-
  • Sulfanilamidothiazole
  • Sulfathiazole(form1)
  • Sulfathiazole(form3)
  • sulfathiazone
  • Sulfavitina
  • Sulfocerol
  • Sulzol
  • Thiacoccine
  • Thiasulfol
  • Thiozamide
  • USAF sn-9
  • usafsn-9
  • Wintrazole
  • SULFATHIAZOLE
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