PG 501 Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Pentona, Tanabe ,Japan ,1978

Manufacturing Process

A mixture of 1.0 g of 6,6,9-trimethyl-9-azabicyclo[3.3.1]nonan-3β-ol, methyl α,α-di-(2-thienyl)-glycolate and 30 mg of metallic sodium is heated at 80°C to 90°C for about 2 hours under reduced pressure. After cooling, ether is added to the reaction mixture. The mixture is extracted with 10% hydrochloric acid. The aqueous layer is alkalified with sodium carbonate and reextracted with ethyl acetate. The extract is washed with water, dried and concentrated to dryness. The residue thus obtained is treated with hydrogen chloride by conventional manner. 2.0 g of the α,α-di-(2-thienyl)glycolate of 6,6,9- trimethyl-9-azabicyclo[3.3.1]nonan-3β-ol hydrochloride are obtained. Yield 83%.

Therapeutic Function

Antiparkinsonian

PG 501 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PG 501 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58

32891-29-5()Verwandte Suche:

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• 2-Thiopheneacetic acid, a-hydroxy-a-2-thienyl-, (1R,3R,5R)-6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, hydrochloride, rel- (9CI)
• 2-Thiopheneacetic acid, a-hydroxy-a-2-thienyl-, 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, hydrochloride, exo-
• 6,6,9-Trimethyl-9-azabicyclo[3.3.1]non-3b-yl a,a-di(2-thienyl)glycolate hydrochloride
• 6,6,9-Trimethyl-9-azabicyclo[3.3.1]nonan-3b-ol a,a-di-2-thienylglycolate (ester) hydrochloride
• 9-Azabicyclo[3.3.1]nonane, 2-thiopheneacetic acid deriv.
• Glycolic acid, di-2-thienyl-, 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester hydrochloride, exo- (8CI)
• KAO 264
• mazaticol hydrochloride
• PG 501
• Pentona
• 32891-29-5
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