2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1)
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- CAS-Nr.
- 659-40-5
- Bezeichnung:
- 2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1)
- Englisch Name:
- Hexamidine diisethionate
- Synonyma:
- SymCalmin;Desomedine;Elestab HP 100;Hexamidine 2-hydroxyethansulfonate;2535RP;HD-100;HP-100;RP-2535;Esomedina;Ophtamedine
- CBNumber:
- CB5901139
- Summenformel:
- C22H32N4O6S
- Molgewicht:
- 480.58
- MOL-Datei:
- 659-40-5.mol
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2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Eigenschaften
- Schmelzpunkt:
- 246-247° (dec)
- Dichte
- 671[at 20℃]
- Dampfdruck
- 0Pa at 20℃
- L?slichkeit
- Sparingly soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride
- Wasserl?slichkeit
- 48.2g/L at 20℃
- InChIKey
- NBVZMBLJRHUOJR-UHFFFAOYSA-N
- SMILES
- C(CO)S(O)(=O)=O.O(C1C=CC(C(N)=N)=CC=1)CCCCCCOC1C=CC(C(N)=N)=CC=1
- LogP
- 4.47 at 25℃
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
RIDADR |
2811 |
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WGK Germany |
3 |
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HazardClass |
6.1(b) |
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PackingGroup |
III |
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Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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Sicherheit |
P264 |
Nach Gebrauch gründlich waschen. |
P264 |
Nach Gebrauch gründlich waschen. |
P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
P273 |
Freisetzung in die Umwelt vermeiden. |
P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
P330 |
Mund ausspülen. |
P391 |
Verschüttete Mengen aufnehmen. |
P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White or slightly yellow powder, hygroscopic
Verwenden
hexamidine diisethionate is an anti-microbial and preservative targeting fungi and yeast. It may also have some emollient capacities.
Kontakt-Allergie
Hexamidine is an antiseptic active against Grampositive
bacteria and fungi, used as a disinfectant and a
preservative in cosmetics. It induces papulo-vesicular
and diffuse allergic contact dermatitis.
Toxikologie
Acute oral LD(50) values of Hexamidine Diisethionate were 0.71 to 2.5 g/kg in mice and 0.75 g/kg in rats. Dermal exposure to 4 g/kg Hexamidine Diisethionate in rats or up to 9.4 ml/kg of a 0.1% Hexamidine Diisethionate solution under occlusion in rabbits produced no mortality or other signs of toxicity. The no-observed-effect level (NOEL) for oral subchronic toxicity of Hexamidine Diisethionate in rats was 50 mg/kg/day. No signs of toxicity were observed with 2% Hexamidine Diisethionate in subchronic studies using rabbits. Application of 0.1 ml of 0.11% Hexamidine Diisethionate in aqueous solution to the eyes of rabbits produced transient reactions; 0.05% produced no reactions. Slight erythema was observed with 0.10% Hexamidine Diisethionate applied to the abraded skin of 1/11 albino rabbits. A 40% solution of Hexamidine Diisethionate applied to 10% of the body surface of rats produced slight erythema, slight edema, and scabbing in some animals at varying times after treatment. Hexamidine Diisethionate was not a sensitizer in the guinea pig maximization test or in an intracutaneous guinea pig sensitization test. Hexamidine Diisethionate was not a photosensitizer in albino rabbits. Hexamidine Diisethionate was not mutagenic in a bacterial reverse mutagenicity assay or clastogenic in mammalian cells. Hexamidine Diisethionate at 0.10% did not provoke primary irritation, inflammation, or sensitization in a clinical test of 200 human subjects
[1].
2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 306)Lieferanten
659-40-5(2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1))Verwandte Suche:
- 2-Hydroxyethanesulphonic acid,compoundwith4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine](2:1)
- Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4-1,6-hexanediylbis(oxy)bisbenzenecarboximidamide (2:1)
- 2-Hydroxyethansulfonsure, Verbindung mit 4,4′-(Hexan-1,6-diylbis(oxy))bis(benzolcarboxamidin) (2:1)
- 2535RP
- Esomedina
- Ophtamedine
- RP-2535
- 4-[6-(4-Carbamimidoylphenoxy)hexoxy]benzenecarboximidamide 2-hydroxyethanesulfonnate (1:2)
- HEXAMIDINE DIISETHIONATE(HD)
- EXAMIDINE DIISETHIONATE
- Hexamidine bis (isethionate) salt
- HEXAMIDINE DIISETHIONATE
- 4,4'-(Hexane-1,6-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate)
- 2-Hydroxyethanesulfonic acid - 4,4'-[1,6-hexanediylbis(oxy)]dibenzenecarboximidamide (1:1)
- 2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
- hexamidine disethionate
- 4,4'-Diamidino-α,ω-diphenoxyhexane isethionate
- Hexamidine isethionate
- Hexamidine diisethionate, HD100,HP100
- Hexamidine diisethionate Hexamidine diisethionate
- HD-100
- HP-100
- 4'-[hexane-1
- 6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
- compound with 4
- Bioactive HD 100
- 2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2
- Hexamidine diisetionate CRS
- RF 2535 {Isethionate}
- High Quality Hexamidine Diisethionate Powder CAS 659-40-5
- 4,4'-(hexane-1,6-diylbis(oxy))dibenzimidamide 2-hydroxyethanesulfonate
- Hexamidine 2-hydroxyethansulfonate
- Desomedine
- Elestab HP 100
- SymCalmin
- hexamidineisetionate
- Hexamidine bis (hydroxyethyl sulfonic acid) salt
- Hexamidine dihydroxyethyl sulfonate (acid value<1)
- 2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
- 659-40-5
- 556-67-5
- C20H26N4O22C2H6O4S
- API