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2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1)

Hexamidine diisethionate Struktur
659-40-5
CAS-Nr.
659-40-5
Bezeichnung:
2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1)
Englisch Name:
Hexamidine diisethionate
Synonyma:
SymCalmin;Desomedine;Elestab HP 100;Hexamidine 2-hydroxyethansulfonate;2535RP;HD-100;HP-100;RP-2535;Esomedina;Ophtamedine
CBNumber:
CB5901139
Summenformel:
C22H32N4O6S
Molgewicht:
480.58
MOL-Datei:
659-40-5.mol

2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Eigenschaften

Schmelzpunkt:
246-247° (dec)
Dichte
671[at 20℃]
Dampfdruck
0Pa at 20℃
L?slichkeit
Sparingly soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride
Wasserl?slichkeit
48.2g/L at 20℃
InChIKey
NBVZMBLJRHUOJR-UHFFFAOYSA-N
SMILES
C(CO)S(O)(=O)=O.O(C1C=CC(C(N)=N)=CC=1)CCCCCCOC1C=CC(C(N)=N)=CC=1
LogP
4.47 at 25℃
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
RIDADR  2811
WGK Germany  3
HazardClass  6.1(b)
PackingGroup  III
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P273 Freisetzung in die Umwelt vermeiden.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P330 Mund ausspülen.
P391 Verschüttete Mengen aufnehmen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White or slightly yellow powder, hygroscopic

Verwenden

hexamidine diisethionate is an anti-microbial and preservative targeting fungi and yeast. It may also have some emollient capacities.

Kontakt-Allergie

Hexamidine is an antiseptic active against Grampositive bacteria and fungi, used as a disinfectant and a preservative in cosmetics. It induces papulo-vesicular and diffuse allergic contact dermatitis.

Toxikologie

Acute oral LD(50) values of Hexamidine Diisethionate were 0.71 to 2.5 g/kg in mice and 0.75 g/kg in rats. Dermal exposure to 4 g/kg Hexamidine Diisethionate in rats or up to 9.4 ml/kg of a 0.1% Hexamidine Diisethionate solution under occlusion in rabbits produced no mortality or other signs of toxicity. The no-observed-effect level (NOEL) for oral subchronic toxicity of Hexamidine Diisethionate in rats was 50 mg/kg/day. No signs of toxicity were observed with 2% Hexamidine Diisethionate in subchronic studies using rabbits. Application of 0.1 ml of 0.11% Hexamidine Diisethionate in aqueous solution to the eyes of rabbits produced transient reactions; 0.05% produced no reactions. Slight erythema was observed with 0.10% Hexamidine Diisethionate applied to the abraded skin of 1/11 albino rabbits. A 40% solution of Hexamidine Diisethionate applied to 10% of the body surface of rats produced slight erythema, slight edema, and scabbing in some animals at varying times after treatment. Hexamidine Diisethionate was not a sensitizer in the guinea pig maximization test or in an intracutaneous guinea pig sensitization test. Hexamidine Diisethionate was not a photosensitizer in albino rabbits. Hexamidine Diisethionate was not mutagenic in a bacterial reverse mutagenicity assay or clastogenic in mammalian cells. Hexamidine Diisethionate at 0.10% did not provoke primary irritation, inflammation, or sensitization in a clinical test of 200 human subjects[1].

2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 306)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shangdong Yuanlitai Nutratech Co.,ltd
+8618782242822
tatiana@yltnutra.com China 8 58
QINGDAO HONG JIN CHEMCIAL CO.,LTD.
532-83657313
hjt@hong-jin.com China 228 58
Beri Pharma Co., Ltd.
+8613417710166
sales@zhberi.com China 227 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
ZhenYiBio Technology Inc
+8615309206328
alexxue@zhenyibio.com China 296 58
Hebei Fengjia New Material Co., Ltd
+86-0311-87836622 +86-17333973358
sales06@hbduling.cn China 8051 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 997 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651
admin@zlchemi.com China 3002 58
Hebei Shengyang Water Conservancy Engineering Co., Ltd.
+8615373025980
clara@hbshengyang.com China 875 58

659-40-5(2-Hydroxyethansulfonsure, Verbindung mit 4,4'-[Hexan-1,6-diylbis(oxy)]bis[benzolcarboxamidin] (2:1))Verwandte Suche:


  • 2-Hydroxyethanesulphonic acid,compoundwith4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine](2:1)
  • Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4-1,6-hexanediylbis(oxy)bisbenzenecarboximidamide (2:1)
  • 2-Hydroxyethansulfonsure, Verbindung mit 4,4′-(Hexan-1,6-diylbis(oxy))bis(benzolcarboxamidin) (2:1)
  • 2535RP
  • Esomedina
  • Ophtamedine
  • RP-2535
  • 4-[6-(4-Carbamimidoylphenoxy)hexoxy]benzenecarboximidamide 2-hydroxyethanesulfonnate (1:2)
  • HEXAMIDINE DIISETHIONATE(HD)
  • EXAMIDINE DIISETHIONATE
  • Hexamidine bis (isethionate) salt
  • HEXAMIDINE DIISETHIONATE
  • 4,4'-(Hexane-1,6-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate)
  • 2-Hydroxyethanesulfonic acid - 4,4'-[1,6-hexanediylbis(oxy)]dibenzenecarboximidamide (1:1)
  • 2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
  • hexamidine disethionate
  • 4,4'-Diamidino-α,ω-diphenoxyhexane isethionate
  • Hexamidine isethionate
  • Hexamidine diisethionate, HD100,HP100
  • Hexamidine diisethionate Hexamidine diisethionate
  • HD-100
  • HP-100
  • 4'-[hexane-1
  • 6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
  • compound with 4
  • Bioactive HD 100
  • 2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2
  • Hexamidine diisetionate CRS
  • RF 2535 {Isethionate}
  • High Quality Hexamidine Diisethionate Powder CAS 659-40-5
  • 4,4'-(hexane-1,6-diylbis(oxy))dibenzimidamide 2-hydroxyethanesulfonate
  • Hexamidine 2-hydroxyethansulfonate
  • Desomedine
  • Elestab HP 100
  • SymCalmin
  • hexamidineisetionate
  • Hexamidine bis (hydroxyethyl sulfonic acid) salt
  • Hexamidine dihydroxyethyl sulfonate (acid value<1)
  • 2-hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1)
  • 659-40-5
  • 556-67-5
  • C20H26N4O22C2H6O4S
  • API
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