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N-(Tri(hydroxymethyl)methyl)glycin

Tricine Struktur
5704-04-1
CAS-Nr.
5704-04-1
Bezeichnung:
N-(Tri(hydroxymethyl)methyl)glycin
Englisch Name:
Tricine
Synonyma:
TRIS-HCL BUFFER;1389475;TROMETHAMINE HYDROCHLORIDE;Ticine;Tricine buffer, free acid;TRI(HYDROXYMETHYL) AMINO METHANE HYDROCHLORIDE;TRICINE;TRIClNE;n-Tricine-D8;Tricine >99%
CBNumber:
CB5853856
Summenformel:
C6H13NO5
Molgewicht:
179.17
MOL-Datei:
5704-04-1.mol

N-(Tri(hydroxymethyl)methyl)glycin Eigenschaften

Schmelzpunkt:
186-188 °C (dec.)
Siedepunkt:
311.69°C (rough estimate)
Dichte
1.05 g/mL at 20 °C
Dampfdruck
0.002-0.004Pa at 20-25℃
Brechungsindex
1.4240 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
L?slichkeit
H2O: 4 M at 20 °C, clear, colorless
Aggregatzustand
crystalline
Farbe
clear colorless (40 % (w/w) in H2O) solution
PH
4.0-6.0 (1M in H2O)
pka
8.1(at 25℃)
S?ure-Base-Indikators(pH-Indikatoren)
7.4 - 8.8
Geruch (Odor)
Odorless
Wasserl?slichkeit
soluble
Merck 
14,9651
BRN 
1937804
Stabilit?t:
Stable.
LogP
-2.87 at 25℃
CAS Datenbank
5704-04-1(CAS DataBase Reference)
EPA chemische Informationen
Glycine, N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]- (5704-04-1)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-36-36/37/39
WGK Germany  3
3
TSCA  Yes
HS Code  29052900
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warnung P264, P305+P351+P338,P337+P313
Sicherheit
P403 An einem gut belüfteten Ort aufbewahren.

N-(Tri(hydroxymethyl)methyl)glycin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Chemische Eigenschaften

White/clear crystalline powder

Verwenden

Good's buffers Tricine is used as an electrophoresis buffer and involved in the separation of low molecular weight proteins and peptides. It operates in the pH range between 7.4 and 8.8. It acts as an effective scavenger of hydroxyl radicals during the study of radiation-induced membrane damage. It is also used in resuspension of cell pellets. It is a zwitterionic amino acid commonly useful in the pH range of 7.4-8.8 and the pKa is 8.05 at 25°C. This buffer is also used as an eluent in asymmetrical flow field-flow fractionation (AFFFF).

Allgemeine Beschreibung

Tricine and its salts are used as biological buffers to control the pH of body fluids in vitro and in vivo. It acts as a precursor for polymers, oxazolones (with carboxylic acids), and oxazolidines (with aldehydes). Trizma can serve as an alkalizing agent in treating acidosis of the blood.

Biologische Aktivit?t

Electrophoresis buffer. Working pH range: 7.4 - 8.8. Commonly used in SDS-PAGE to seperate peptides. Also used in other electrophoresis methods, high performance liquid chromatography and ion exchange chromatopgraphy.

l?uterung methode

Crystallise Tricine from EtOH and water. [Good et al. Methods Enzymol 24B 53 1968, McGothlin & Jordan Analyt Lett 9 245 1976, Beilstein 18 III/IV 3454.]

N-(Tri(hydroxymethyl)methyl)glycin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


N-(Tri(hydroxymethyl)methyl)glycin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 211)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Fortuna Chemical Co., Ltd
+86-027-59207850
info@fortunachem.com China 5975 58
Suzhou Genemill Biotechnology Co.,Ltd
+8615862502491
aimeegao@genemill.com China 39 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12835 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5857 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
Hebei Weibang Biotechnology Co., Ltd
+8617732866630
bess@weibangbio.com China 18151 58
Apeloa production Co.,Limited
+8619933239880
admin@apcl.com.cn China 852 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 18751 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Neostar United (Changzhou) Industrial Co., Ltd.
+86-0519-85551759 +8613506123987
marketing1@neostarunited.com China 8838 58

5704-04-1(N-(Tri(hydroxymethyl)methyl)glycin)Verwandte Suche:


  • LABOTEST-BB LT00454966
  • n-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-glycin
  • TRICINE
  • TRIMETHYLOLAMINOMETHANE HYDROCHLORIDE
  • TRIClNE
  • E-Z 96 SIZE SELECT-IT (1 X 96)
  • TRIZMA(R) HYDROCHLORIDE
  • TROMETHANE HCL
  • N-[2-HYDROXY-1,1-BIS(HYDROXYMETHYL)ETHYL]GLYCINE
  • MOLE-READY-TRIS
  • N-[TRIS(HYDROXYMETHYL)METHYL]GLYCINE
  • SPECTRIS(R) HYDROCHLORIDE
  • SPECTRIS(TM) HYDROCHLORIDE
  • N-(tri(hydroxymethyl)methyl)glycine
  • Tricine, Molecular Biology Grade N-Tris(hydroxymethyl)methylglycine, Molecular Biology Grade
  • Tricine, ULTROL Grade
  • TRICINE, BIOTECHNOLOGY PERFORMANCE CERTI FIED
  • TRICINE SIGMAULTRA
  • TRICINE 1M SOLUTION, BIOTECHNOLOGY PERFO
  • Tricine(N-Tris-(Hydroxymethyl)
  • Tricine, 98+%
  • Tricine, for biochemistry, 98%
  • TRICINE, BIOPERFORMANCE CERTIFIED, C
  • Tricine, for biochemistry, 99+%
  • n-Tricine-D8
  • N-[2-hydroxy-1,1-bis(hydroxyme
  • Glycine, N-2-hydroxy-1,1-bis(hydroxymethyl)ethyl-
  • N-tris(Hydroxymethyl)methylglycine (TRICINE)
  • TRICINE ULTRAPURE
  • Tricine >99%
  • N-[Tris(hydroxymethyl)methyl]glycine [Good's buffer component for biological research]
  • N-TRIS(HYDROXYMETHYL) METHLGLYCINE extrapure
  • tris hydrochloride solution
  • Trizma(R) hydrochloride solution
  • Tris Buffer substance, Tris(hydroxymethyl)aminomethane Buffer substance
  • 1,3-Dihydroxy-2-(hydroxymethyl)propan-2-ylaminoacetic acid
  • Carboxymethylaminomethylidynetrimethanol
  • TRIS(HYDROXYMETHYL)AMINOMETHANE, HCL
  • TRIS(HYDROXYMETHYL)AMINOMETHANE HYDROCHLORIDE BUFFER SOLUTION
  • TRIS(HYDROXYMETHYL)METHYLAMINE HYDROCHLORIDE
  • TRIS(HYDROXYMETHYL)METHYLAMMONIUM CHLORIDE
  • TRIS(HYDROXYMETHYL) METHYLGLYCINE
  • TRISMAT(R) HYDROCHLORIDE
  • TRISMAT(TM) HYDROCHLORIDE
  • TROMETAMOL HYDROCHLORIDE
  • N-[1,1-Bis(hydroxymethyl)-2-hydroxyethyl]glycine
  • N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]glycine
  • Tricine Vetec(TM) reagent grade, >=99%
  • Trizma? hydrochloride buffer solution
  • Trizma? Buffer substance
  • Tricine,99+%,for biochemistry
  • Tricine,98%,for biochemistry
  • Tricine [Good's buffer component for biological research]
  • Tricine 
  • Tricine, for biocheMistry, 98% 100GR
  • Tricine, for biocheMistry, 98% 250GR
  • Tricine, for biocheMistry, 98% 25GR
  • Tricine, for biocheMistry, 99+% 100GR
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