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Dermorphin

Dermorphin Struktur
77614-16-5
CAS-Nr.
77614-16-5
Englisch Name:
Dermorphin
Synonyma:
DERMORPHIN;Dermorphin HAc;Dermorphin Powder;DERMORPHIN ACETATE;dermorphin/DERMORPHIN ACETATE;Dermorphin trifluoroacetate salt;L-Tyr-D-Ala-L-Phe-Gly-L-Tyr-L-Pro-L-Ser-NH2;Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide;(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-carbamoyl-2-hydro;(2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide
CBNumber:
CB5498044
Summenformel:
C40H50N8O10
Molgewicht:
802.87
MOL-Datei:
77614-16-5.mol

Dermorphin Eigenschaften

Schmelzpunkt:
157-159 °C
Siedepunkt:
1323.8±65.0 °C(Predicted)
Dichte
1.363±0.06 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
Soluble in DMSO
Aggregatzustand
powder
pka
9.83±0.15(Predicted)
Farbe
white to off-white
Sequenz
H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2
InChIKey
FHZPGIUBXYVUOY-VWGYHWLBSA-N
SMILES
C(N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N)(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](C)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)CC1C=CC=CC=1)CC1C=CC(O)=CC=1

Sicherheit

WGK Germany  3

Dermorphin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Dermorphin was first isolated from the skin of the skin of South American frogs of the genus Phyllomedusa.  It is a high potency natural opiate peptide that binds selectively to mu-opioid receptors.

Verwenden

A mu-opioid receptor agonist

Nebenwirkungen

Like μ-opiate agonists, dermorphins produce antinociception and also catalepsy, respiratory depression, constipation, tolerance, and dependence, although at a lower degree than morphine does[1].

Dermorphin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dermorphin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 118)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Xinsheng New Material Technology Co., LTD.
+86-16632316109
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Hebei Weimiao Import and Export Trade Co., Ltd.
+86-19948166995 +86-19948166995
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Hebei Xunou new energy Technology Co., LTD
+86-17531957005; +undefined17531957005
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Strong peptide cross-border e-commerce Co. LTD
+undefined13930052870
 qt01@qiangtaipharm.com China 84 58
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+8615354498258
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  • DERMORPHIN ACETATE
  • L-Tyr-D-Ala-L-Phe-Gly-L-Tyr-L-Pro-L-Ser-NH2
  • Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide
  • Dermorphin trifluoroacetate salt
  • Dermorphin Powder
  • (2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide
  • Dermorphin HAc
  • (2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-carbamoyl-2-hydro
  • DERMORPHIN
  • dermorphin/DERMORPHIN ACETATE
  • 77614-16-5
  • 77614-16-5
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