2-[(2-amino-5-methylph2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium saltenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n
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- CAS-Nr.
- 73630-23-6
- Englisch Name:
- 2-[(2-amino-5-methylph2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium saltenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n
- Synonyma:
- QUIN 2;QUIN-2;Quin II (potassium);ium Salt Calbiochem;Quin-2 (potassium salt);QUIN 2, TetrapotaßQUIN 2, TETRAPOTASSIUM SALT;QUIN 2, Tetrapotassium Salt - CAS 73630-23-6 - Calbiochem;2-[[2-BIS(CARBOXYMETHYL)AMINO-5-METHYLPHENOXY]METHYL]-6-METHOXY-8-BIS(CARBOXYMETHYL)AMINOQUINOLINE, 4K;2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium salt
- CBNumber:
- CB5479434
- Summenformel:
- C26H28KN3O10
- Molgewicht:
- 581.62
- MOL-Datei:
- 73630-23-6.mol
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2-[(2-amino-5-methylph2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium saltenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n Eigenschaften
- Schmelzpunkt:
- >250℃
- RTECS-Nr.
- MB8303000
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: soluble10mg/mL
- Aggregatzustand
- powder
- Farbe
- Light yellow
- Wasserl?slichkeit
- Soluble in water at 10mg/ml
- maximale Wellenl?nge (λmax)
- 353 nm, 333 nm
- Merck
- 13,8130
- BRN
- 5374262
- Biologische Anwendungen
- Calcium indicator; cadmium indicator; iron indicator; lanthanum indicator; zinc indicator; identifying taste modulators
2-[(2-amino-5-methylph2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium saltenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Quin-2 is a high-affinity fluorescent calcium indicator (K
d = 115 nM for calcium). It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation/emission maxima for quin-2 are 339 and 492 nm, respectively.
Verwenden
2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium salt can be used as a fluorescent highly selective Ca2+ indicator exhibiting fast uptake and release of Ca2+. Used as a calibration substance in the measurement of cytoplasmic free calcium.
Allgemeine Beschreibung
Binding of Ca
2+ to QUIN 2 leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield. TPEN (Cat. No. 616394) can be used in conjunction with QUIN 2 to reduce heavy-metal quenching of QUIN 2 fluorescence in cells. Spectral properties in the presence of low calcium concentrations (ex. 354 nm, em. 510 nm) differ from those during high calcium conditions (ex. 332 nm, em. 505 nm).
2-[(2-amino-5-methylph2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium saltenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-[(2-amino-5-methylph2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium saltenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 51)Lieferanten
73630-23-6()Verwandte Suche:
- QUIN-2
- QUIN 2, TETRAPOTASSIUM SALT
- 2-[(2-AMINO-5-METHYLPHENOXY)METHYL]-6-METHOXY-8-AMINO-QUINOLINE-N,N,N',N'-TETRAACETIC ACID TETRAPOTASSIUM SALT
- 2-[[2-BIS-(CARBOXYMETHYL)AMINO-5-METHYLPHENOXY]-METHYL]-6-METHOXY-8-BIS-(CARBOXYMETHYL)AMINOQUINOLINE TETRAPOTASSIUM SALT
- 2-[[2-BIS(CARBOXYMETHYL)AMINO-5-METHYLPHENOXY]METHYL]-6-METHOXY-8-BIS(CARBOXYMETHYL)AMINOQUINOLINE, 4K
- 2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrapotassium salt
- 2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,Nμ,Nμ-tetraacetic acid tetrapotassium salt, 2-{[2-Bis-(carboxymethyl)amino-5-methylphenoxy]-methyl}-6-methoxy-8-bis-(carboxymethyl)aminoquinoline tetrapotassium salt
- N-[2-[[8-[Bis(carboxymethyl)amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-N-(carboxymethyl)glycine tetrapotassium salt
- QUIN 2
- 2-{[2-Bis-(carboxymethyl)amino-5-methylphenoxy]-methyl}-6-methoxy-8-bis-(carboxymethyl)aminoquinoline tetrapotassium salt
- Glycine, N-(2-((8-(bis(carboxymethyl)amino)-6-methoxy-2-quinolinyl)methoxy)-4-methylphenyl)-N-(carboxymethyl)-, tetrapotassium salt
- Glycine,N-[2-[[8-[bis(carboxymethyl)amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-N-(carboxymethyl)
- 2-[(2-amino-5-methylphenoxy)methyl]-
6-methoxy-8-aminoquinoline-n,n,n0,n0-tetraacetic
acid Tetrapotassium Salt
- Quin-2 (potassium salt)
- QUIN 2, Tetrapotassium Salt - CAS 73630-23-6 - Calbiochem
- 2-[(2-amino-5-methylph2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n,n-tetraacetic acid tetrapotassium saltenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n
- ium Salt Calbiochem
- QUIN 2, Tetrapotaß
- Quin II (potassium)
- 73630-23-6
- C26H23K4N3O10
- Biochemicals and Reagents
- BioChemical
- Fluorescent Probes, Labels, Particles and Stains
- Detection
- Quinoline
