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Arbidol hydrochloride

Arbidol hydrochloride Struktur
131707-23-8
CAS-Nr.
131707-23-8
Englisch Name:
Arbidol hydrochloride
Synonyma:
Abidol;Doxetine;ARBIDOL HCL;Abiduoer.HCI;Arbidole HCl;Umifenovir HCl;yansuanabiduoer;Soluble Arbidol;Arbidol hydrochlorid;ARBIDOL HYDROCHLORIDE
CBNumber:
CB5438596
Summenformel:
C22H26BrClN2O3S
Molgewicht:
513.88
MOL-Datei:
131707-23-8.mol

Arbidol hydrochloride Eigenschaften

Schmelzpunkt:
133-137?C
storage temp. 
-20°C
L?slichkeit
DMSO: soluble20mg/mL protein, clear
Aggregatzustand
powder
Farbe
white to beige
Stabilit?t:
Hygroscopic
InChI
InChI=1S/C22H25BrN2O3S.ClH/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;/h6-11,26H,5,12-13H2,1-4H3;1H
InChIKey
OMZHXQXQJGCSKN-UHFFFAOYSA-N
SMILES
C(C1=C(N(C)C2=CC(Br)=C(O)C(CN(C)C)=C12)CSC1C=CC=CC=1)(=O)OCC.Cl
CAS Datenbank
131707-23-8(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/38
S-S?tze: 26
WGK Germany  3
Toxizit?t guinea pig,LD50,oral,> 3gm/kg (3000mg/kg),Drugs of the Future. Vol. 17, Pg. 1079, 1992.
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P332+P313 Bei Hautreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P337+P313 Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

Arbidol hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Umifenovir is a broad-spectrum antiviral agent. It inhibits the replication of H5N1 influenza (IC50 = 30 μg/ml) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro (IC50 = 3.537 μM). Umifenovir inhibits entry of hepatitis C virus (HCV) pseudoparticles in Huh7 cells (IC50 = 6 μg/ml) and inhibits Zika virus protein synthesis in Vero cells. In vivo, umifenovir (45 mg/kg) reduces the formation of influenza-induced lung lesions in ferrets.

Chemische Eigenschaften

Off White to Pale Yellow Solid

Verwenden

Arbidol hydrochloride (ARB) is a small monocular compound. It is used to prevent severe pneumonia and virus-associated cytokine dysregulation induced by influenza viruses (IFV). ARB also possesses some immunomodulatory properties, including the effects of interferon induction and macrophage activation.
Arbidol is a broad-spectrum antiviral that has demonstrated activity against a number of enveloped and non-enveloped viruses, and is used clinically to treat influenza. Arbidol inhibits viral entry into host cell and stimulates immune response. Arbidol inhibits fusion between the viral capsid and the cell membrane of the target cell, thus preventing viral entry.

Arbidol hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Arbidol hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 444)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Guangzhou TongYi biochemistry technology Co.,LTD
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+86-13131129325
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131707-23-8()Verwandte Suche:


  • 1H-INDOLE-3-CARBOXYLIC ACID, 6-BROMO-4-[(DIMETHYLAMINO)METHYL]-5-HYDROXY-1-METHYL-2-[(PHENYLTHIO)METHYL]-, ETHYL ESTER, MONOHYDROCHLORIDE
  • 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1h-indole-3-carboxylic acid ethyl ester monohydrochloride
  • ARBIDOL HCL
  • ARBIDOL HYDROCHLORIDE
  • Arbidol hydrochloride hydrate
  • ARBIDOLHYDROCHLORIDE(FORR&DONLY)
  • HYDROCHLORIDEOFETHYL6-BROMO-4-((DIMETHYLAMINO)METHYL)-5.
  • 1h-indole-3-carboxylic acid, 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-, ethyl ester, monohydrochloride, hydrate
  • 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-,1H-indole-3-carboxylic Acid Ethyl Ester Hydrochloride
  • 6-bromo-4-[(dimethykamino)methyl]-5-hydroxy-1-methyl-2[(phenylthio)-methy]-1H-indol-3-carboxylata hydrochloride
  • Abiduoer.HCI
  • 6-bromo-4-(dimethylaminomethyl)-5-hydroxy-1-methyl-2-[(phenylthio)methyl]indole-3-carboxylic acid ethyl ester hydrate hydrochloride
  • ethyl 6-bromo-4-(dimethylaminomethyl)-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate hydrate hydrochloride
  • Arbidol & Arbidol Hydrochloride
  • ethyl 6-broMo-4-[(diMethylaMino)Methyl]-5-hydroxy-1-Methyl-2-[(phenylsulfanyl)Methyl]-1H-indole-3-carboxylate hydrochloride
  • Ethyl 6-broMo-4-((diMethylaMino)Methyl)-5-hydroxy-1-Methyl-2-((phenylthio)Methyl)-1H-indole-3-carboxylate hydrochloride
  • Ethyl 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-car
  • 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic acid ethyl ester, hydrochloride (1:1)
  • Arbidol hydrochloride 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic acid ethyl ester monohydrochloride
  • Arbidol Hydrochloride solution,100ppm
  • Ethyl 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-
  • Arbidole HCl
  • (3S,4S,5R)-5-(hydroxymethyl)dihydrofuran-2,2,3,4(3H)-tetraol hydrochloride
  • Arbidol hydrochloride###131707-23-8
  • Doxetine
  • Arbidol hydrochloride (Umifenovir hydrochloride)
  • Arbidol HCl 131707-23-8
  • yansuanabiduoer
  • Arbidol hydrochloride, Umifenovir
  • ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate,hydrochloride
  • Soluble Arbidol
  • Arbidol/Arbidol hydrochloride/Arbidol hcl
  • Umifenovir hydrochloride
  • Abidol
  • Arbidol/Umifenovir Hydrochloride
  • hot selling Sultamicillin
  • Arbidol hydrochloride USP/EP/BP
  • Arbidol HCl (Umifenovir)
  • 99% Pure Pharmaceutical Grade CAS 131707-23-8 Arbidol HCl/Arbidol Hydrochloride
  • Umifenovir (Arbidol) HCl
  • Arbidol-d6Q: What is Arbidol-d6 Q: What is the CAS Number of Arbidol-d6
  • Arbidol hydrochlorid
  • 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-, ethyl ester, hydrochloride (1:1)
  • Umifenovir HCl
  • 131707-23-8
  • 31707-23-8
  • C22H25BrN2O3SHClH2O
  • C22H25BrN2O3SHCl
  • C22H26BrClN2O3S
  • C22H25BrN2O3SClH
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  • 131707-23-8
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