Sp-Cyclic AMPS (sodium salt) Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Several cyclic nucleotide phosphodiesterases (PDE2, -
5, -
6, -
10, and -
11) contain a tandem of GAF domains in their N-
terminal regulatory region that are thought to mediate cAMP-
or cGMP-
induced stimulation of adenylyl and guanylyl cyclases. Sp-
cyclic AMPS (Sp-
cAMPS) is a derivative of cAMP that binds the PDE10 GAF domain (EC
50 = 40 μM). It has been used to study GAF-
mediated stimulation of PDE10.
Sp-Cyclic AMPS (sodium salt) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte