PCI 34051
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- CAS-Nr.
- 950762-95-5
- Englisch Name:
- PCI 34051
- Synonyma:
- PCI-34051;PCI 34051;PCI-34051 ，S2012;PCI-34051;PCI 34051;PCI-34051, 10 mM in DMSO;N-hydroxy-1-(4-Methoxybenzyl)-1H-indole-6-carboxaMide;1-(4-methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide;N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide;N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide;1H-Indole-6-carboxamide, N-hydroxy-1-[(4-methoxyphenyl)methyl]-
- CBNumber:
- CB52622953
- Summenformel:
- C17H16N2O3
- Molgewicht:
- 296.32
- MOL-Datei:
- 950762-95-5.mol
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PCI 34051 Eigenschaften
- Dichte
- 1.25
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- L?slichkeit
- insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL in DMSO
- Aggregatzustand
- Powder
- pka
- 9.16±0.30(Predicted)
- Farbe
- White to gray
- InChI
- InChI=1S/C17H16N2O3/c1-22-15-6-2-12(3-7-15)11-19-9-8-13-4-5-14(10-16(13)19)17(20)18-21/h2-10,21H,11H2,1H3,(H,18,20)
- InChIKey
- AJRGHIGYPXNABY-UHFFFAOYSA-N
- SMILES
- N1(CC2=CC=C(OC)C=C2)C2=C(C=CC(C(NO)=O)=C2)C=C1
PCI 34051 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast.
PCI 34051 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
PCI 34051 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 151)Lieferanten
950762-95-5()Verwandte Suche:
- N-hydroxy-1-(4-Methoxybenzyl)-1H-indole-6-carboxaMide
- PCI 34051
- PCI-34051
- 1-(4-methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide
- 1H-Indole-6-carboxamide, N-hydroxy-1-[(4-methoxyphenyl)methyl]-
- N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide
- PCI-34051;PCI 34051
- N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
- PCI-34051, 10 mM in DMSO
- PCI-34051 ，S2012
- 950762-95-5
- Apoptosis
- Aromatics
- Heterocycles
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Inhibitor
