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N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-)

N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-) Struktur
7722-44-3
CAS-Nr.
7722-44-3
Englisch Name:
N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-)
Synonyma:
Colistin A;Colistin IV;Polymixin E1;Polymyxin E1;Colistin A-d5 Discontinued;XQKABMNFUQVRFN-SADGAIANSA-N;Colistin A Pentafluoroacetate;Polymyxin E1-[13C6,15N] TFA salt;N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-);N2-(6-Methyl-1-oxooctyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-)
CBNumber:
CB52245444
Summenformel:
C53H100N16O13
Molgewicht:
1169.46
MOL-Datei:
7722-44-3.mol

N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-) Eigenschaften

alpha 
225461 -93.3° (2% acetic acid)
Siedepunkt:
1536.8±65.0 °C(Predicted)
Dichte
1.25±0.1 g/cm3(Predicted)
L?slichkeit
Methanol (Very Slightly), Water (Slightly)
Aggregatzustand
Solid
pka
13.08±0.70(Predicted)
Farbe
White to Pale Beige

Sicherheit

N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-) Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Colistin A is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.

Definition

ChEBI: A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus.

N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • Colistin A
  • N2-(6-Methyl-1-oxooctyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-)
  • N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Leu-L-Leu-L-A2bu-L-A2bu-L-Thr-)
  • Polymyxin E1
  • XQKABMNFUQVRFN-SADGAIANSA-N
  • Colistin A-d5 Discontinued
  • Colistin IV
  • Polymixin E1
  • Polymyxin E1-[13C6,15N] TFA salt
  • Colistin A Pentafluoroacetate
  • 7722-44-3
  • Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
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