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LOPRAZOLAM

LOPRAZOLAM Struktur
61197-93-1
CAS-Nr.
61197-93-1
Englisch Name:
LOPRAZOLAM
Synonyma:
Loprazolam;UTEFBSAVJNEPTR-XMHGGMMESA-N;1H-Imidazo(1,2-A)(1,4)benzodiazepin-1-one, 6-(2-chlorophenyl)-2,4-dihydro-2-((4-methyl-1-piperazinyl)methylene)-8-nitro-, methanesulphonate
CBNumber:
CB52130896
Summenformel:
C24H25ClN6O6S
Molgewicht:
561.01
MOL-Datei:
61197-93-1.mol

LOPRAZOLAM Eigenschaften

Sicherheit

DEA Controlled Substances CSCN: 2773
CAS SCH: IV
NARC: N

LOPRAZOLAM Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Avlane,J.A.S.M.,France,1981

Manufacturing Process

1.1 g of methanesulfonic acid were added dropwise to a mixture of 4.6 g of 8- nitro-1,2-dihydro-2-(N-methylpiperazin-1-yl)methylene-6-(o-chlorophenyl)- 1H,4H-imidazo-[1,2-a][1,4]benzodiazepin-1-one in 100 ml of anhydrous methylene chloride and 5 ml of methanol. Dry ether was slowly added until crystals formed on scratching and the solution was allowed to crystallize with further ether being added to complete the crystallization. The pale yellow solid was filtered off, washed with ether and crystallized from methylene chloridemethanol to obtain 5.4 g of 8-nitro-1,2-dihydro-2-(N-methylpiperazin-1- yl)methylene-6-(o-chlorophenyl)-1H,4H-imidazo-[1,2-a][1,4]-benzodiazepin-1- one methanesulfonate melting at 205°C to 210°C.

Therapeutic Function

Tranquilizer

LOPRAZOLAM Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


  • 1H-Imidazo(1,2-A)(1,4)benzodiazepin-1-one, 6-(2-chlorophenyl)-2,4-dihydro-2-((4-methyl-1-piperazinyl)methylene)-8-nitro-, methanesulphonate
  • Loprazolam
  • UTEFBSAVJNEPTR-XMHGGMMESA-N
  • 61197-93-1
  • C23H21ClN6O3xCH4O3S
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