ANTICytoplasmic FMR1 interacting protein 2 (CYFIP2), ANTIp53-inducible mRNA (PIR121) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-PIR121 antibody produced in rabbit may be used in immunoblotting.
Allgemeine Beschreibung
Cytoplasmic FMR1 interacting protein 2 (PIR121) (CYFIP2) is a vital constituent of the Wiskott?Aldrich Syndrome protein (WASp) ?family verprolin?homologous protein (WAVE) regulatory complex. PIR121/CYFIP2 is a close homolog of CYFIP1 (p140Sra), with a sequence identity of 88%. The CYFIP2 gene is mapped to human chromosome 5q33.3
Biochem/physiol Actions
Cytoplasmic FMR1 interacting protein 2 (PIR121) (CYFIP2) is capable of interacting with fragile X mental retardation protein (FRMP) and also FRMP related proteins like, Fragile X related protein 1 and 2 (FXR1P and FXR2P). CYFIP2 helps to modulate spinal morphology and presynaptic activity. De novo hotspot variations in this gene is associated with early?onset epileptic encephalopathy.
ANTICytoplasmic FMR1 interacting protein 2 (CYFIP2), ANTIp53-inducible mRNA (PIR121) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte