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Cyclohexanecarboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-, cis-

Cyclohexanecarboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-, cis- Struktur
2778223-52-0
CAS-Nr.
2778223-52-0
Englisch Name:
Cyclohexanecarboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-, cis-
Synonyma:
Pralsetinib Impurity 2;cis-1-Methoxy-4-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexanecarboxylic acid;Cis cyclohexane carboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-;Cyclohexanecarboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-, cis-
CBNumber:
CB512220444
Summenformel:
C17H23N5O3
Molgewicht:
345.4
MOL-Datei:
2778223-52-0.mol

Cyclohexanecarboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-, cis- Eigenschaften

Siedepunkt:
597.6±50.0 °C(Predicted)
Dichte
1.32±0.1 g/cm3(Predicted)
pka
4.23±0.44(Predicted)
InChI
InChI=1S/C17H23N5O3/c1-10-8-13(19-14-9-11(2)21-22-14)20-15(18-10)12-4-6-17(25-3,7-5-12)16(23)24/h8-9,12H,4-7H2,1-3H3,(H,23,24)(H2,18,19,20,21,22)/t12-,17-
InChIKey
QKVACMCXFIAPPC-QASKLWRZSA-N
SMILES
[C@]1(OC)(C(O)=O)CC[C@H](C2=NC(NC3C=C(C)NN=3)=CC(C)=N2)CC1

Sicherheit

Cyclohexanecarboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-, cis- Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Cyclohexanecarboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-, cis- could be used to synthesise Pralsetinib which is a RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer.

Cyclohexanecarboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-, cis- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Cyclohexanecarboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-, cis- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 11)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Unibest Industrial Co.,Ltd.
+86-8657427855777 +86-18758850676
 info@unibestcn.com China 227 58
Shanghai jing Hao pharmaceutical technology co., LTD 021-68900963 15618693615
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Shanghai Boc Chemical Co.,Ltd 021-34975603-808 18721111801
 sales@bocpharma.com China 998 64
SHANGHAI FDC-CHEMICAL CO.,LTD 021-61469567 13482353728
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Henan Alfachem Co.,Ltd. 0371-0371-55051623 18137891487
 2853979817@qq.com China 9945 58
Shanghai Yanze Chemical Co., Ltd. 021-13773155751 19975051755
 260924549@qq.com China 8913 58
Unibest Pharmaceutical Technology Co., Ltd. 13735578103
 baipeng@unibestpharma.com China 135 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 17717813675;
 malulu@leyan.com China 39990 58
Shanghai Easy CDMO Co.,Ltd 021-61734564
August@easycdmo.com China 10030 58
Henan Vcommend Consultrading Co., Ltd. 13393721940; 13393721940
 sales@vcommend.com China 10005 58
  • Cyclohexanecarboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-, cis-
  • Cis cyclohexane carboxylic acid, 1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]-
  • cis-1-Methoxy-4-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexanecarboxylic acid
  • Pralsetinib Impurity 2
  • 2778223-52-0
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