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Emulsifyingwax

Emulsifyingwax Struktur
8014-38-8
CAS-Nr.
8014-38-8
Englisch Name:
Emulsifyingwax
Synonyma:
Emulsifying wax BP;Emulsifying Wax (Anionic)
CBNumber:
CB51073527
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Emulsifyingwax Eigenschaften

L?slichkeit
Soluble in chloroform, ether and, on warming, in fixed oils and mineral oil. The PhEur 6.2 specifies that cetostearyl alcohol, emulsifying (type A and type B) are soluble in hot water giving an opalescent solution, practically insoluble in cold water, and slightly soluble in ethanol (96%). The BP 2009 specifies that emulsifying wax is practically insoluble in water (forms an emulsion); partly soluble in ethanol (96%).

Sicherheit

Emulsifyingwax Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

An almost white or pale yellow colored, waxy solid or flakes which when warmed become plastic before melting. Anionic emulsifying wax has a faint characteristic odor and a bland taste.

Vorbereitung Methode

Anionic emulsifying wax is prepared by melting cetostearyl alcohol and heating to about 95℃. Sodium lauryl sulfate, or some other suitable anionic surfactant, and purified water are then added. The mixture is heated to 115℃ and, while this temperature is maintained, the mixture is stirred vigorously until any frothing ceases. The wax is then rapidly cooled.

Pharmazeutische Anwendungen

Anionic emulsifying wax is used in cosmetics and topical pharmaceutical formulations primarily as an emulsifying agent. The wax is added to fatty or paraffin bases to facilitate the production of oil-in-water emulsions that are nongreasy. In concentrations of about 2%, emulsions are pourable; stiffer emulsions, e.g. aqueous cream BP, may contain up to 10% of anionic emulsifying wax.
Creams should be adequately preserved and can usually be sterilized by autoclaving. A better-quality emulsion is produced by incorporating some alkali into the aqueous phase, although care should be taken not to use an excess.
Anionic emulsifying wax (3–30%) may also be mixed with soft and liquid paraffins to prepare anhydrous ointment bases such as emulsifying ointment BP. A preparation of 80% anionic emulsifying wax in white soft paraffin has been used as a soap substitute in the treatment of eczema.
In addition, anionic emulsifying wax (10%) has been added to theobroma oil (cocoa butter) to produce a suppository base with a melting point of 34℃.

Sicherheit(Safety)

Anionic emulsifying wax is used primarily in topical pharmaceutical formulations and is generally regarded as a nontoxic and nonirritant material. However, sodium lauryl sulfate, a constituent of anionic emulsifying wax, is known to be irritant to the skin at high concentrations; sodium cetyl sulfate is claimed to be less irritating.
Emulsifying ointment BP, which contains anionic emulsifying wax, has been found to have major sunscreen activity in clinically normal skin and should therefore not be used before phototherapy procedures.

Lager

Solid anionic emulsifying wax is chemically stable and should be stored in a well-closed container in a cool, dry place.

Inkompatibilit?ten

Incompatibilities of anionic emulsifying wax are essentially those of sodium alkyl sulfates and include cationic compounds ( quaternary ammonium compounds, acriflavine, ephedrine hydrochloride, antihistamines, and other nitrogenous compounds), salts of polyvalent metals (aluminum, zinc, tin, and lead), and thioglycolates. Anionic emulsifying wax is compatible with most acids above pH 2.5. It is also compatible with alkalis and hard water.
Iron vessels should not be used when heating anionic emulsifying wax; stainless steel containers are satisfactory.

Regulatory Status

Included in the FDA Inactive Ingredients Database (rectal emulsions and aerosol foams; topical aerosols, emulsions, creams, lotions, and ointments). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Emulsifyingwax Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Emulsifyingwax Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 5)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Yime New Material Technology Co., Ltd.
+86-66697723 +86-17703311139
admin@china-yime.com China 563 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021
lisa@kingfinertech.com China 3009 58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.
+8618950047208
ellena@amitychem.com China 1176 58
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