Naratriptan Hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Naramig was launched in Germany, Sweden and the UK for use in migraine. It is chemically available via a number of related synthetic routes all having about three steps starting from 5-bromoindole. It is a new serotonin 5-HT_1B/1D receptor antagonist with modest affinity for 5-HT_1a, and very weak affinity for 5-HT₃ receptors. It has little or no affinity for a wide range of non-serotonin receptors including a- and padrenoceptors, dopamine, neurokinin NK₁, and opiate receptors. It mediates vasoconstriction in cerebral vasculature (extra cerebral intracranial vessels), reduces neurogenic inflammation, and inhibits responses mediated by the trigeminal nerves. It has a 6- and 3-fold greater affinity for 5-HT_1B, and 5-HT_1D, receptors, respectively, than sumatriptan which translates to a 2-3 fold increase in potency. The reoccurance of headache was less compared to sumatriptan, zolmitriptan and rizatriptan. Naramig had no clinical effects on blood pressure or heart rate, had a long duration of action with very good tolerability, and has high oral bioavailability.

Chemische Eigenschaften

Beige Solid

Verwenden

Naratriptan Hydrochloride is a triptan drug and is used for the treatment of migraine headaches

Naratriptan Hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Naratriptan Hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
TopScience Biochemical	00852-68527855	info@itopbiochem.com	China Hong Kong	902	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14426	58

143388-64-1()Verwandte Suche:

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• NARATRIPTAN HYDROCHLORIDE (125 MG)F0C3600.998MG/MG(AI)
• Amerge.
• Naramig
• Naratriptan Hydrochloride
• N-Methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide Hydrochloride
• N-Methyl-3-(1-methylpiperidin-4-yl)-1H-indole-5-ethanesulfonamide hydrochloride
• Naratriptan monohydrochloride
• Naratriptan Hydrochloride (125 mg)
• 1H-Indole-5-ethanesulfonaMide,N-Methyl-3-(1-Methyl-4-piperidinyl
• N-Methyl-2-(3-(1-Methylpiperidin-4-yl)-1H-indol-5-yl)ethanesulfonaMide hydrochloride
• Nariptan Hydrochloride
• Naratriptan Nitrate USP
• 1H-Indole-5-ethanesulfonaMide,N-Methyl-3-(1-Methyl-4-piperidinyl)-, hydrochloride (1:1)
• GR-85548A
• N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride
• 1H-Indole-5-ethanesulfonamide,N-methyl-3-(1-methyl-4-piperidinyl)-,hydrochloride
• NARATRIPTAN HYDROCHLORIDE (125 MG)F0C36099%8MG/MG(AI)
• GR-85548A hydrochloride
• Naratriptan Hydrochloride USP/EP/BP
• Naratryptan hydrochloride
• Naratriptan HCl (GR-85548A HCl)
• Naratriptan HydrochlorideQ: What is Naratriptan Hydrochloride Q: What is the CAS Number of Naratriptan Hydrochloride Q: What is the storage condition of Naratriptan Hydrochloride
• Naratriptan Hydrochloride (1457469)
• N-Methyl-2-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)ethane-1-sulfonamide hydrochloride
• 2-[3-(1-Methyl- piperidin-4-yl) -1H-indol-5-yl]- ethanesulfonic acid methylamide. Hydrochloride, USP
• 143388-64-1
• C17H25N3O2SHCl
• C17H25N3O2SClH
• C17H26ClN3O2S
• Amerge, Naramig
• Pharmaceuticals
• Inhibitors
• APIs
• Intermediates & Fine Chemicals