8-bromo-Cyclic ADP-Ribose (sodium salt) Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD
+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, which in turn activate ryanodine receptors. 8-bromo-cADP-Ribose is a stable, cell-permeable analog that blocks calcium release evoked by cADP-ribose in sea urchin egg homogenates with an IC
50 value of 1.7 μM. It is commonly used to investigate intracellular signaling through cADP-ribose in isolated cells and tissues.
8-bromo-Cyclic ADP-Ribose (sodium salt) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte