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REVEROMYCIN A

REVEROMYCIN A Struktur
134615-37-5
CAS-Nr.
134615-37-5
Englisch Name:
REVEROMYCIN A
Synonyma:
REVEROMYCIN A;ZESGNAJSBDILTB-OXVOKJAASA-N;Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
CBNumber:
CB4443481
Summenformel:
C36H52O11
Molgewicht:
660.79
MOL-Datei:
134615-37-5.mol

REVEROMYCIN A Eigenschaften

Siedepunkt:
849.0±65.0 °C(Predicted)
Dichte
1.21±0.1 g/cm3(Predicted)
storage temp. 
−20°C
L?slichkeit
DMF: soluble
Aggregatzustand
solid
pka
4.36±0.17(Predicted)
Farbe
tan

Sicherheit

WGK Germany  3

REVEROMYCIN A Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption.

REVEROMYCIN A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

REVEROMYCIN A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 60)Lieferanten
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Alfa Chemistry 1-516-6625404
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720
 psaitong@jm-bio.com China 12306 58
Lynnchem 86-(0)29-85992781 17792393971
 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890
 info@novachemistry.com United Kingdom 4381 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58

134615-37-5()Verwandte Suche:

  • REVEROMYCIN A
  • ZESGNAJSBDILTB-OXVOKJAASA-N
  • Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
  • 134615-37-5
  • C36H52O11
  • BioChemical
  • Antibiotics
  • Antibiotics A to Z
  • Antibiotics N-S
  • Epidermal Growth Factor Receptor (EGFR)Antibiotics
  • Interferes with Protein Synthesis
  • Antibiotics
  • Antibiotics A to
  • Antibiotics by Application
  • Antibiotics N-SAntibiotics
  • AntifungalAntibiotics
  • Mechanism of Action
  • Receptor Tyrosine Kinase Inhibitors
  • Spectrum of Activity
  • Antineoplastic and Immunosuppressive AntibioticsReceptor Tyrosine Kinase Biology
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