1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R11:Leichtentzündlich.
R34:Verursacht Ver?tzungen.

S-S?tze Betriebsanweisung:

S16:Von Zündquellen fernhalten - Nicht rauchen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Physikalische Eigenschaften

bp 100–103°C/13 mmHg; d 0.824 g cm?3.

Verwenden

1,4-Bis(dimethylamino)-1,1,4,4-tetramethyldisilethylene is used as a reagent for the protection of primary amines with lower pKa values, such as substituted anilines, as their tetramethyldisilylazacyclopentane or Stabase adduct; precursor of tetramethyldisilylthiacyclopentane, a sulfur transfer reagent.
The title reagent is used for the preparation of Stabase derivatives of primary amines, and is particularly useful for the protection of primary aromatic amines with pKa values of 10–11. The protection of substituted anilines is achieved by heating equimolar amounts of the title compound and the anilines in the presence of zinc iodide (0.5 mol %) under a slow stream of nitrogen at 140°C for 5 h. In many cases the products can be purified by vacuum distillation. Cleavage of the Stabase adducts to the corresponding primary amines can be performed in ether in the presence of 2 equiv of methanol and a small amount of p-toluenesulfonic acid monohydrate (0.2 mol %). The tetramethyldisilylazacyclopentane or Stabase adduct (3) is a particularly attractive protecting group due to its ease of preparation, base stability, and facile removal (eq 1).

synthetische

the reagent is prepared as a colorless liquid in 90% yield by treating commercially available bis(chlorodimethylsilyl) ethane with 5 equiv of dimethylamine in ether at 0°C for 5 h.

1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18751	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14426	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
Alfa Chemistry		Info@alfa-chemistry.com	United States	24072	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9984	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20284	58

91166-50-6()Verwandte Suche:

---

• 1,1'-ETHYLENEBIS(N,N,1,1-TETRAMETHYLSILANAMIDE)
• 1,1'-ETHYLENEBIS(N,N,1,1-TETRAMETHYLSILANAMINE)
• 1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE
• 1,4-BIS(DIMETHYLAMINO)-1,1,4,4-TETRAMETHYL-1,4-DISILABUTANE
• BIS(DIMETHYLAMINODIMETHYLSILYL)ETHANE
• 1,2-Bis[(dimethylamino)dimethylsilyl]ethane [Protecting Reagent for Aromatic Primary Amines]
• 1,2-bis((diethylamino)dimethylsilyl)ethane
• 1,1μ-Ethylenebis(N,N,1,1-tetramethylsilanamine), 1,4-Bis(dimethylamino)-1,1,4,4-tetramethyl-1,4-disilabutane, 2,5-Bis(dimethylamino)-2,5-dimethyl-2,5-disilahexane
• α,α'-Ethylenebis(N,N,α,α-tetramethylsilanamine)
• 2,5-Bis(dimethylamino)-2,5-dimethyl-2,5-disilahexane
• [Protecting Reagent for Aromatic Primary Amines]
• 1,2-Bis[(dimethylamino)dimethylsilyl]ethane 
• N-[2-[dimethylamino(dimethyl)silyl]ethyl-dimethylsilyl]-N-methylmethanamine
• 1,2-Bis[(dimethylamino)dimethylsilyl]ethane [Protecting Reagent for Aromatic Primary Amines]>
• Silanamine, 1,1'-(1,2-ethanediyl)bis[N,N,1,1-tetramethyl-
• 1,1'-(Ethane-1,2-diyl)bis(N,N,1,1-tetramethylsilanamine)
• DK424
• 1,1'-(Ethane-1,2-diyl)bis(N,N,1,1-tetramethylsilanamine)
• 91166-50-6
• -CH2SiCH32NCH322
• C10H28N2Si2
• Protection & Derivatization Reagents (for Synthesis)
• Si-N Compounds
• Si (Classes of Silicon Compounds)
• Aminosilanes
• Organometallic Reagents
• Organosilicon
• Others
• Organosilicon
• Others
• Aminosilanes
• Protection & Derivatization Reagents (for Synthesis)
• Si (Classes of Silicon Compounds)
• Si-N Compounds
• Synthetic Organic Chemistry
• Chemical Synthesis
• Organometallic Reagents