L-Isoserine
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- CAS-Nr.
- 632-13-3
- Englisch Name:
- L-Isoserine
- Synonyma:
- L-ISOSERINE;(S)-LSOSERINE;(S)-ISOSERINE;L-Isoserine>L-Isoserine USP/EP/BP;(S)-2-HYDROXY-B-ALANINE;(s)-2-hydroxy-β-alanine;Terbutaline Impurity 60;(-)-3-Amino-L-lactic acid;(S)-2-HYDROXY-BETA-ALANINE
- CBNumber:
- CB4394257
- Summenformel:
- C3H7NO3
- Molgewicht:
- 105.09
- MOL-Datei:
- 632-13-3.mol
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L-Isoserine Eigenschaften
- Schmelzpunkt:
- 199~201℃
- Siedepunkt:
- 386.6±27.0 °C(Predicted)
- Dichte
- 1.415±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Aggregatzustand
- powder to crystal
- pka
- pK1:2.72(＋1);pK2:9.25(0) (25°C,μ=0.16)
- Farbe
- White to Almost white
- Wasserl?slichkeit
- Slightly soluble in water.
- Sensitive
- Moisture Sensitive
- InChI
- InChI=1S/C3H7NO3/c4-1-2(5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
- InChIKey
- BMYNFMYTOJXKLE-REOHCLBHSA-N
- SMILES
- C(O)(=O)[C@@H](O)CN
- CAS Datenbank
- 632-13-3(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| F |
10-21 |
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| HS Code |
2922500090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
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L-Isoserine Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.
Biologische Aktivit?t
Research has found that L-isoserine showed the ability to inhibit Aminopeptidase N (APN) at a half-maximal inhibitory concentration (IC50 ) value of 563 μM, which could serve as a new lead compound for further chemical modification and optimization. In addition, it has been reported that L-isoserine-L-leucine dipeptide shows moderate aminopeptidase B inhibitory activity (IC50 of 140 μM). This evidence indicates that the incorporation of an amino acid to L-isoserine may contribute to its inhibitory activity against APN. L-isoserine induces long-lasting effects by increasing the expression of GAT3 (glial GABA transporte) in peri-infarct regions[1-2].
L-Isoserine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
L-Isoserine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 212)Lieferanten
632-13-3()Verwandte Suche:
- (S)-ISOSERINE
- (S)-2-HYDROXY-B-ALANINE
- (S)-2-HYDROXY-BETA-ALANINE
- (S)-3-AMINO-2-HYDROXYPROPIONIC ACID
- L-ISOSERINE
- (s)-2-hydroxy-β-alanine
- (S)-LSOSERINE
- (2S)-3-AMINO-2-HYDROXY-PROPANOIC ACID
- (-)-3-Amino-L-lactic acid
- (S)-3-Amino-2-hydroxypropanoic acid
- (S)-2-Hydroxy-β-alanine, (S)-3-Amino-2-hydroxypropionic acid
- L-Isoserine>
- Propanoic acid, 3-amino-2-hydroxy-, (2S)-
- (2S)-3-amino-2-hydroxypropanoicaci
- L-Isoserine USP/EP/BP
- Terbutaline Impurity 60
- 632-13-3
- 288-16-5
- 632-11-1632-13-3
- 632-13-2
- Specialty Synthesis
- Serine Derivatives
- Unnatural Amino Acid Derivatives
- Peptide Synthesis
- (intermediate of isepamicin)
